Department of Drug Management and Policy, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Ishikawa, Japan.
Trop Med Int Health. 2010 May;15(5):639-44. doi: 10.1111/j.1365-3156.2010.02494.x. Epub 2010 Mar 1.
To assess the prevalence of counterfeit anthelminthic medicines in Cambodia, and to determine influential factors.
Commonly used anthelminthic medicines were collected from private drug outlets. Medicines were carefully observed including their registration labelling, and their authenticity was investigated with the manufacturers and the Medicines Regulatory Authorities. Samples were analysed by High-Performance Liquid Chromatography at the National Health Product Quality Control Centre, Cambodia.
Two hundred and three samples of anthelminthics were collected from 137 drug stores. Domestic products constituted 36.9%. Of 196 samples which were verified for registration, 15.8% were not registered. Of 165 samples successfully investigated for their authenticity, 7 (4.2%) were identified as counterfeit. All of these medicines were purchased in open packs or containers, and most of them were foreign manufactured and/or without registration.
The results of our survey urge strict implementation of drug registration and vigilance on the availability of unregistered medicines to combat counterfeit medicines in Cambodia.
评估柬埔寨假冒驱虫药品的流行情况，并确定其影响因素。
从私人药店收集常用的驱虫药品。仔细观察药品，包括其注册标签，并与制造商和药品监管机构一起调查其真实性。在柬埔寨国家卫生产品质量控制中心，采用高效液相色谱法对样品进行分析。
从 137 家药店共收集了 203 份驱虫药样本。国产产品占 36.9%。在 196 份经过注册验证的样本中，有 15.8%未注册。在成功调查了 165 个样本的真实性后，发现有 7 个（4.2%）被鉴定为假冒产品。所有这些药品都是在开放包装或容器中购买的，其中大部分是外国制造的，或没有注册。
我们的调查结果表明，迫切需要严格执行药品注册，并警惕未注册药品的供应，以打击柬埔寨的假冒药品。
