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间隙保持器中镍和铬的生物降解:一项体外研究。

Biodegradation of nickel and chromium from space maintainers: an in vitro study.

作者信息

Bhaskar V, Subba Reddy V V

机构信息

Department of Pedodontics and Preventive Dentistry, Ahmedabad Dental College, Bhadaj, Rancodpura Road, Kalol, Ahmedabad, Gujrat, India.

出版信息

J Indian Soc Pedod Prev Dent. 2010 Jan-Mar;28(1):6-12. doi: 10.4103/0970-4388.60484.

Abstract

Band materials are often used in the practice of pediatric dentistry. Nickel and Chromium are the main ingredients of these materials. The potential health hazards of nickel and chromium and their compounds have been the focus of attention for more than 100 years. It has established that these metals could cause hypersensitivity. The study was undertaken to analyze in vitro biodegradation of space maintainers made out of stainless steel band materials from manufacturers Dentaurum and Unitek. The leaching effect simulating the use of one, two, three, and four space maintainers in clinical practice was studied by keeping the respective number of space maintainers in the artificial saliva incubating at 37 degrees C and analyzing for nickel and chromium release after 1,7,14,21 and 28 days using atomic absorption spectrophotometer. Results showed that there was measurable release of both nickel and chromium which reached maximum level at the end of 7 days which was statistically significant (P < 0.05) and was very much below the dietary average intake even for four bands used and was not capable of causing any toxicity.

摘要

带环材料在儿童牙科实践中经常被使用。镍和铬是这些材料的主要成分。镍和铬及其化合物对健康的潜在危害在100多年来一直是人们关注的焦点。已经证实这些金属会引起过敏反应。本研究旨在分析由Dentaurum和Unitek制造商生产的不锈钢带环材料制成的间隙保持器的体外生物降解情况。通过将相应数量的间隙保持器置于37℃的人工唾液中孵育,并使用原子吸收分光光度计分析1、7、14、21和28天后镍和铬的释放情况,研究了模拟临床实践中使用一个、两个、三个和四个间隙保持器的浸出效果。结果表明,镍和铬均有可测量的释放,在第7天末达到最高水平,具有统计学意义(P<0.05),即使使用四个带环,其释放量也远低于饮食平均摄入量,并且不会引起任何毒性。

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