Babayigit Arzu, Olmez Duygu, Sozmen Sule C, Makay Balahan, Uzuner Nevin, Karaman Ozkan, Anal Ozden, Gulay Zeynep
Departments of Pediatric, and daggerMicrobiology, Dokuz Eylul University Hospital, Balcova, Izmir, Turkey.
Pediatr Emerg Care. 2010 Mar;26(3):203-5. doi: 10.1097/PEC.0b013e3181d1e3f7.
Nocardia farcinica infections are rare and potentially life threatening. Herein, we describe a case of pulmonary nocardiosis caused by N. farcinica. This 13-year-old girl admitted with 1-year history of cough, intermittent fever, and recurrent hemoptysis. She was examined for multiple pulmonary nodules mimicking pulmonary metastasis that were detected with chest radiography and computed tomography of the thorax. Eventually, N. farcinica was yielded in culture of sputum and aspiration material of pulmonary nodules. No predisposing factor could be shown for Nocardia infection. Although infections caused by N. farcinica have tendency to disseminate, and are mostly resistant to antibiotics, the patient was successfully treated with prolonged intravenous antibiotic therapy followed with oral amoxicillin-clavulanate.
鼻疽诺卡菌感染罕见且可能危及生命。在此,我们描述一例由鼻疽诺卡菌引起的肺诺卡菌病病例。这名13岁女孩因咳嗽、间歇性发热和反复咯血1年入院。胸部X线和胸部计算机断层扫描检查发现多个类似肺转移的肺结节。最终,在痰液和肺结节穿刺材料培养中培养出鼻疽诺卡菌。未发现诺卡菌感染的诱发因素。尽管鼻疽诺卡菌引起的感染有播散倾向,且大多对抗生素耐药,但该患者通过延长静脉抗生素治疗后口服阿莫西林-克拉维酸成功治愈。