Department of Ophthalmology, People's Hospital, Peking University, Beijing, China.
Retina. 2010 Mar;30(3):447-51. doi: 10.1097/IAE.0b013e3181d374a5.
The purpose of this study was to evaluate the long-term results of vitreoretinal surgery without use of intraocular silicone oil or gas in patients with proliferative diabetic retinopathy and tractional retinal detachment.
A clinical interventional case-series study was conducted of 168 eyes of 150 patients with diabetic tractional retinal detachment who were consecutively treated by pars plana vitrectomy without endotamponade during a study period of 7 years. Per selection criterion, retinal defects did not develop or were not observed in any of the study participants before or during surgery. The surgery included pars plana vitrectomy, removal of epiretinal membranes, and retinal endolaser coagulation. Combined cataract surgery was performed in 33 eyes (20%). The mean follow-up was 23 + or - 14 months (range, 12-65 months).
In 158 eyes (94%), the retina reattached after surgery and remained attached until the end of follow-up. Subretinal fluid absorbed completely within 2 months after surgery. Best-corrected visual acuity improved in 126 eyes (75%) and remained unchanged in 19 eyes (11%). Mean best-corrected visual acuity improved from 2.22 + or - 1.22 at baseline to 1.24 + or - 1.00 at final follow-up (P < 0.001). At the end of follow-up, 11 eyes (7%) showed iris neovascularization, and 9 of these 11 eyes developed iris neovascularization after surgery. In multivariate logistic regression, the only factor associated with postoperative rubeosis iridis was preexisting rubeosis iridis (odds ratio, 6.4).
Vitreoretinal surgery for tractional retinal detachment in proliferative diabetic retinopathy may not necessarily be combined with an ocular endotamponade if there were no pre- or intraoperative retinal breaks.
本研究旨在评估在增殖性糖尿病视网膜病变伴牵拉性视网膜脱离患者中,不使用眼内硅油或气体进行玻璃体视网膜手术后的长期效果。
对 7 年期间连续接受经平坦部玻璃体切除术治疗、术中未行眼内填充的 150 例 168 只眼的糖尿病牵拉性视网膜脱离患者进行了一项临床干预性病例系列研究。根据入选标准,所有研究对象在术前和术中均未发生或未发现视网膜裂孔。手术包括经平坦部玻璃体切除术、切除视网膜内膜和视网膜光凝。33 只眼(20%)联合行白内障手术。平均随访 23±14 个月(范围 12-65 个月)。
158 只眼(94%)术后视网膜复位,直至随访结束时仍保持在位。术后 2 个月内视网膜下液完全吸收。126 只眼(75%)最佳矫正视力提高,19 只眼(11%)保持不变。平均最佳矫正视力从基线时的 2.22±1.22 提高至最终随访时的 1.24±1.00(P<0.001)。随访结束时,11 只眼(7%)出现虹膜新生血管,其中 9 只眼在术后出现虹膜新生血管。多变量逻辑回归分析显示,与术后新生血管性青光眼相关的唯一因素是术前存在新生血管性青光眼(比值比,6.4)。
在增殖性糖尿病视网膜病变伴牵拉性视网膜脱离患者中,如果术前或术中无视网膜裂孔,玻璃体视网膜手术不一定需要联合眼内填充。