de Vasconcelos Carvalho Marianne, do Nascimento George João Ferreira, Andrade Emerson, Andrade Mariana, Sobral Ana Paula Veras
Oral Pathology, Federal University of Rio Grande do Norte, Natal, RN, Brazil.
J Craniofac Surg. 2010 Mar;21(2):436-9. doi: 10.1097/SCS.0b013e3181cfe917.
Parry-Romberg syndrome (PRS) is an uncommon degenerative condition characterized by a slow, progressive, and, generally, unilateral atrophy of facial tissues, including muscles, bones and skin. Ophthalmological and neurological manifestations have frequently been observed and few oral changes have been reported. This article reports a case of PRS in a 22-year-old woman, exhibiting facial asymmetry, hypoplasia of the right side of the face, areas of skin hyperpigmentation, and oral alterations, involving the mandible and teeth. These clinical and radiological findings led to the diagnosis of PRS. In an attempt to improve the patient's facial aesthetic and the dental functions, oral pentoxifylline, orthodontic rehabilitation, and subcutaneous injections of polymethylmethacrylate microspheres were used as part of the treatment for the facial atrophy. Together, these approaches accounted for a minimal invasive treatment with long term satisfactory results.
帕里-罗姆伯格综合征（PRS）是一种罕见的退行性疾病，其特征为面部组织（包括肌肉、骨骼和皮肤）缓慢、进行性且通常为单侧性萎缩。常观察到眼科和神经学表现，而口腔变化的报道较少。本文报告一例22岁女性的PRS病例，该患者表现出面部不对称、右侧面部发育不全、皮肤色素沉着区域以及涉及下颌骨和牙齿的口腔改变。这些临床和放射学检查结果导致了PRS的诊断。为改善患者的面部美观和牙齿功能，采用口服己酮可可碱、正畸修复以及皮下注射聚甲基丙烯酸甲酯微球作为面部萎缩治疗的一部分。这些方法共同构成了一种微创治疗，取得了长期满意的效果。
