Yim Sunjin, Yang Il-Hyung, Baek Seung-Hak
Department of Orthodontics, School of Dentistry, Seoul National University, Seoul, Korea.
Department of Orthodontics, Dental Research Institute, School of Dentistry, Seoul National University, Seoul, Korea.
Korean J Orthod. 2020 Nov 25;50(6):407-417. doi: 10.4041/kjod.2020.50.6.407.
To investigate the dental phenotypes and treatment modalities (Tx- Mod) in Korean patients with Parry-Romberg syndrome (PRS) using longitudinal data.
The samples consisted of 10 PRS patients, who were treated and/or followed-up at Seoul National University Dental Hospital between 1998 and 2019. Using a novel PRS severity index based on the numbers of the atrophy-involved area and asymmetry-involved item, we classified them into mild (n = 3), moderate (n = 2), and severe (n = 5). Dental phenotypes, including congenitally missing tooth (Con-Missing-Tooth), microdontia, tooth with short root (Short-Root), tooth with dilacerated root, and delayed eruption/impacted tooth, were investigated along with Tx-Mod.
The side of occurrence of all dental phenotypes showed 100% concordance with the side of PRS involvement. The most two common dental phenotypes were Con-Missing- Tooth and Short-Root (n = 29 and n = 17 in six patients). The sums of the average number of Con-Missing-Tooth and Short-Root increased from mild PRS to moderate PRS and severe PRS cases (1.0, 6.0, and 6.2). In terms of Tx- Mod, growth observation due to mild atrophy, fixed orthodontic treatment, and grafting were used for mild PRS cases. Tx-Mod for moderate PRS cases involved growth observation for surgery due to an early age at the initial visit. For severe PRS cases, diverse Tx-Mod combinations including unilateral functional appliance, fixed orthodontic treatment, growth observation, grafting, and orthognathic surgery were used.
The novel PRS severity index may be useful to provide primary data for individualized diagnosis and treatment planning for PRS patients.
利用纵向数据研究韩国帕里-罗姆伯格综合征（PRS）患者的牙齿表型及治疗方式（Tx-Mod）。
样本包括10例PRS患者，于1998年至2019年期间在首尔国立大学牙医院接受治疗和/或随访。我们基于萎缩累及区域数量和不对称累及项目构建了一个新的PRS严重程度指数，将患者分为轻度（n = 3）、中度（n = 2）和重度（n = 5）。对牙齿表型进行了研究，包括先天性缺牙（Con-Missing-Tooth）、过小牙、短根牙（Short-Root）、牙根弯曲牙以及萌出延迟/阻生牙，并分析了相应的Tx-Mod。
所有牙齿表型的发生侧与PRS累及侧的一致性为100%。最常见的两种牙齿表型是先天性缺牙和短根牙（6例患者中分别为29颗和17颗）。先天性缺牙和短根牙的平均数量总和从轻度PRS到中度PRS再到重度PRS病例逐渐增加（分别为1.0、6.0和6.2）。在Tx-Mod方面，轻度萎缩患者进行生长观察，轻度PRS病例采用固定正畸治疗和植骨术。中度PRS病例的Tx-Mod包括因初诊年龄小而进行手术生长观察。对于重度PRS病例，采用了多种Tx-Mod组合，包括单侧功能矫治器、固定正畸治疗、生长观察、植骨术和正颌手术。
新的PRS严重程度指数可能有助于为PRS患者的个体化诊断和治疗计划提供基础数据。
