Salgado J P, Khoramnia R, Schweiger B, Lohmann C, Winkler von Mohrenfels C
Klinik und Poliklinik für Augenheilkunde, Klinikum rechts der Isar, München.
Klin Monbl Augenheilkd. 2010 Dec;227(12):966-70. doi: 10.1055/s-0028-1109955. Epub 2010 Mar 9.
The aim of this study was to evaluate the six-month clinical results of the light adjustable lens (LAL).
In 20 eyes of 12 patients with cataract a cataract surgery with implantation of a light adjustable lens has been performed. 2 ¹/₂ weeks after surgery all intraocular lens adjustments were carried out. Preoperatively, immediately before the adjustment procedures and 1 month, 3 and 6 months after the adjustment procedure a complete ophthalmic examination was performed.
All cataract surgeries have been carried out without any complications. 2 ¹/₂ weeks after surgery the mean spherical equivalent was + 0.39 D (standard deviation [SD] ± 0.79 D). 6 months after the adjustment procedure the spherical equivalent was -0.07 D (SD ± 0.25 D). 6 months after the adjustment procedure all patients were within ± 0.5 D of intended refraction. Two weeks after surgery the mean cylinder was -0.82 D (SD ± 0.67 D) and was reduced after the adjustments to -0.14 D (SD ± 0.30 D).
The light adjustable lens is a new IOL with the ability to correct up to two dioptres of sphere and cylinder after implantation. Our clinical results are promising. Especially the astigmatic correction is very promising, but further clinical investigations with larger patient numbers and longer follow-up are necessary.
本研究旨在评估可调节人工晶状体（LAL）的六个月临床效果。
对12例白内障患者的20只眼进行了植入可调节人工晶状体的白内障手术。术后2 ¹/₂周进行了所有人工晶状体的调整。术前、调整手术前即刻以及调整手术后1个月、3个月和6个月进行了全面的眼科检查。
所有白内障手术均未出现任何并发症。术后2 ¹/₂周平均球镜等效度为 +0.39 D（标准差[SD]±0.79 D）。调整手术后6个月，球镜等效度为 -0.07 D（SD±0.25 D）。调整手术后6个月，所有患者的屈光度均在预期屈光度±0.5 D范围内。术后2周平均柱镜为 -0.82 D（SD±0.67 D），调整后降至 -0.14 D（SD±0.30 D）。
可调节人工晶状体是一种新型人工晶状体，植入后能够矫正高达2屈光度的球镜和柱镜。我们的临床结果很有前景。尤其是散光矫正非常有前景，但需要更多患者数量和更长随访时间的进一步临床研究。
