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配药错误的发生率、类型及原因:文献综述

Incidence, type and causes of dispensing errors: a review of the literature.

作者信息

James K Lynette, Barlow Dave, McArtney Rowena, Hiom Sarah, Roberts Dave, Whittlesea Cate

机构信息

Pharmacy Department, King's College London, London.

出版信息

Int J Pharm Pract. 2009 Feb;17(1):9-30.

Abstract

OBJECTIVES

To identify, review and evaluate the published literature on the incidence, type and causes of dispensing errors in community and hospital pharmacy.

METHOD

Electronic databases were searched from 1966 to February 2008. This was supplemented by hand-searching the bibliographies of retrieved articles. Analysis of the findings explored the research methods, operational definitions, incidence, type and causes of dispensing errors.

KEY FINDINGS

Sixty papers were identified investigating dispensing errors in the UK, US, Australia, Spain and Brazil. In general, the incidence of dispensing errors varied depending on the study setting, dispensing system, research method and operational definitions. The most common dispensing errors identified by community and hospital pharmacies were dispensing the wrong drug, strength, form or quantity, or labelling medication with the incorrect directions. Factors subjectively reported as contributing to dispensing errors were look-alike, sound-alike drugs, low staffing and computer software. High workload, interruptions, distractions and inadequate lighting were objectively shown to increase the occurrence of dispensing errors.

CONCLUSIONS

Comparison of the reviewed studies was confounded by differences in study setting, research method and operational definitions for dispensing errors, error rate and classification of error types. The World Health Organization is currently developing global patient safety taxonomy. Such a standardized taxonomy for dispensing errors would facilitate consistent data collection and assist the development of error-reduction strategies.

摘要

目的

识别、回顾和评估已发表的关于社区药房和医院药房调配差错的发生率、类型及原因的文献。

方法

检索了1966年至2008年2月的电子数据库,并通过手工检索所检索文章的参考文献进行补充。对研究结果的分析探讨了研究方法、操作定义、调配差错的发生率、类型及原因。

主要发现

共识别出60篇关于英国、美国、澳大利亚、西班牙和巴西调配差错的研究论文。总体而言,调配差错的发生率因研究环境、调配系统、研究方法和操作定义的不同而有所差异。社区药房和医院药房识别出的最常见调配差错包括发放错误的药品、剂量、剂型或数量,或用错误的说明给药品贴标签。主观报告的导致调配差错的因素有外形相似、发音相似的药品、人员配备不足和计算机软件问题。客观显示高工作量、干扰、分心和照明不足会增加调配差错的发生。

结论

由于研究环境、研究方法以及调配差错、差错率和差错类型分类的操作定义存在差异,所回顾研究之间的比较受到了混淆。世界卫生组织目前正在制定全球患者安全分类法。这样一种针对调配差错的标准化分类法将有助于进行一致的数据收集,并有助于制定减少差错策略。

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