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[喉声门区早期癌的治疗功能结果]

[Functional results of treatment of early carcinoma in the glottic region of the larynx].

作者信息

Milovanović J P, Djukić V B, Milovanović A P, Trivić A S, Baljosević I S, Vukasinović M M, Milovanović A

机构信息

Klinika za ORL i maksilofacijalnu hirurgiju KCS, Beograd.

出版信息

Acta Chir Iugosl. 2009;56(3):95-100. doi: 10.2298/aci0903095m.

Abstract

Early stage glottic cancer can be successfully treated with open surgery, LASER surgery or radiotherapy. During this treatment the physician obviously has to bear in mind principles of oncological radicality, but also, none the less, the preservation of all the functions of the larynx, and especially the preservation of voice quality. The aim of the study is to compare, in a specifically designed prospective study, the method of treatment with the functional results of basic characteristics of spoken voice of patients with early stage cancer of the glottis region. Then, based on the analysis of the results, to try and determine the most successful method of treatment. The first study group consisted of 72 patients operated using transoral laser microsurgery; the second study group consisted of 75 patients operated using open surgery; and the third study group consisted of 74 patients treated with radiotherapy. The voice quality is much better after laser chordectomy compared to open surgery chordectomy with reconstruction. Furthermore, the functional results of voice quality, after a laser chordectomy, are worse when compared to the group of patients treated with radiotherapy. Taking into account all objective and subjective phoniatric parameters, we determined that there is no crucial difference in the voice quality of patients operated using laser chordectomy and patients primarily treated with radiotherapy. From a functional point of view these two methods are superior to open surgery chordectomy.

摘要

早期声门癌可通过开放手术、激光手术或放射治疗成功治疗。在这种治疗过程中,医生显然必须牢记肿瘤根治性原则,但同时也必须保留喉部的所有功能,尤其是嗓音质量。本研究的目的是在一项专门设计的前瞻性研究中,比较声门区早期癌症患者的治疗方法与语音基本特征的功能结果。然后,根据结果分析,试图确定最成功的治疗方法。第一研究组由72例接受经口激光显微手术的患者组成;第二研究组由75例接受开放手术的患者组成;第三研究组由74例接受放射治疗的患者组成。与开放手术声带切除术加重建相比,激光声带切除术后的嗓音质量要好得多。此外,与放射治疗组相比,激光声带切除术后嗓音质量的功能结果更差。考虑到所有客观和主观的发声参数,我们确定接受激光声带切除术的患者与主要接受放射治疗的患者在嗓音质量上没有关键差异。从功能角度来看,这两种方法优于开放手术声带切除术。

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