[声门上型喉癌患者的隐匿性转移]

[Occult metastases in patients with supraglottic larynx cancer].

作者信息

Djordjević V Z, Dimitrijević M V, Jesić S D, Petrović Z M, Arsović N A, Milovanović J P, Nesić V S

机构信息

Medicinski fakultet, Institut za ORL i maksilofacijalnu hirurgiju KC Srbije, Beograd.

出版信息

Acta Chir Iugosl. 2009;56(3):117-20. doi: 10.2298/aci0903117d.

DOI:10.2298/aci0903117d

PMID:20218115

Abstract

The treatment of patients with supraglottic laryngeal cancer still remains a controversal issue. The study comprised 193 patients with a supraglottic laryngeal carcinoma treated in the period 1986-2003. All patients had primary surgery. They all had clinically and ultrasonografically negative findings in the neck (N0). Bilateral selective neck dissection at the level II-III was performed in all patients at the time of primar surgery. Postoperative radiotherapy was given to all patients with verified occult metastases (60 Gy). The occult cervical node metastases were found in 18% (35/193). Ipsilateral occult metastases were more common (77%, 27/35), but both bilateral and contralateral spread was also seen (14%, 5/35 and 9%, 3/35, respectively). Only in two (1%) did metastases develop subsequently. The 5-years survival rate was 86%.

摘要

声门上型喉癌患者的治疗仍是一个有争议的问题。该研究纳入了1986年至2003年期间接受治疗的193例声门上型喉癌患者。所有患者均接受了初次手术。他们在颈部的临床和超声检查结果均为阴性（N0）。所有患者在初次手术时均进行了双侧II - III级选择性颈清扫术。所有经证实有隐匿性转移的患者（60 Gy）均接受了术后放疗。隐匿性颈部淋巴结转移的发生率为18%（35/193）。同侧隐匿性转移更为常见（77%，27/35），但双侧和对侧转移也有发生（分别为14%，5/35和9%，3/35）。只有两例（1%）随后发生了转移。5年生存率为86%。