McDermott Nancy E, Barrett John, Hipp Jason, Merino Maria J, Richard Lee Chyi-Chia, Waterman Paige, Domingo Demetrio L, Walsh Thomas J
National Institute of Dental and Craniofacial Research, Bethesda, Maryland 20892, USA.
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2010 Mar;109(3):e64-9. doi: 10.1016/j.tripleo.2009.11.012.
Mucormycosis is an aggressive and potentially devastating fungal infection which typically manifests in pulmonary, rhinocerebral, or disseminated forms in patients with hematologic malignancy. Mucormycosis confined to the periodontium is uncommon, and to our knowledge only 6 cases have been reported in the English-language literature. This case report describes a patient with acute leukemia and periodontal mucormycosis. Calcofluor fluorescence microscopy is also proposed as a method for establishing a prompt diagnosis and guiding extent of intraoperative surgical debridement.
毛霉菌病是一种侵袭性且可能具有毁灭性的真菌感染,通常在血液系统恶性肿瘤患者中表现为肺部、鼻脑型或播散型。局限于牙周组织的毛霉菌病并不常见,据我们所知,英文文献中仅报道过6例。本病例报告描述了一名患有急性白血病和牙周毛霉菌病的患者。还提出将荧光钙白显微镜检查作为一种方法,用于快速诊断并指导术中手术清创的范围。