• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

牙科诊所中毛霉菌病的诊断与管理:印度口腔健康专业人员指南

Diagnosis and management of mucormycosis in the dental clinic: A guide for oral health professionals in India.

作者信息

Aswal Gunjan S, Rawat Renu, Dwivedi Dhara, Prabhakar Nitin, Kumar K R Vinod

机构信息

School of Dentistry, Faculty of Medical Sciences, The University of West Indies, St Augustine, Trinidad and Tobago.

Private Practitioner, Bangalore, Karnataka, India.

出版信息

J Family Med Prim Care. 2022 Aug;11(8):4293-4298. doi: 10.4103/jfmpc.jfmpc_1373_21. Epub 2022 Aug 30.

DOI:10.4103/jfmpc.jfmpc_1373_21
PMID:36353040
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9638618/
Abstract

With the current pandemic raging over the world, science and medicine is faced with hereto with unfought enemies or less fought opponent in the form of viruses and consequently, other biotic entities. While researchers are striving to identify and conquer the variants of COVID-19, other innocuous organisms are raising their ugly heads in the form of opportunistic fungal infections. Mucormycosis/Black Fungus is an invasive opportunistic fungal infection caused by species. It spreads through blood vessels causing thrombosis, ischemia, and necrosis. Population with pre-existing immunocompromised conditions such as Diabetes Mellitus, Malignancy, Long-term immunosuppressant therapy are more susceptible. Mucormycosis associated with Corona Virus Disease-2019 (COVID-19) proved to be catastrophic due to its high mortality rates. Rhino orbital Mucormycosis is the most common form. The primary care physician, being the first and often, (more so in developing countries) and being the only point of contact with a healthcare professional, plays a pivotal role in the diagnosis and management of this condition. The keystone to decreasing mortality is early detection and diagnosis followed by preventive measures to control progression to the brain. A multidisciplinary approach by various specialties is a prerequisite for effective diagnosis and management. Antifungal therapy, surgical debridement, and resection of the affected areas are protocols to be followed. Post-operative defects cause impairment of function, phonetics, and esthetics. Prosthetic rehabilitation of these defects has shown favorable results, especially in the aged and immunocompromised individuals.

摘要

随着当前这场大流行病在全球肆虐,科学和医学面临着前所未有的敌人,或者说是以病毒以及其他生物实体形式出现的较少被对抗的对手。当研究人员努力识别和攻克新冠病毒变种时,其他无害生物正以机会性真菌感染的形式抬头。毛霉菌病/黑真菌病是一种由多种真菌引起的侵袭性机会性真菌感染。它通过血管传播,导致血栓形成、局部缺血和坏死。患有如糖尿病、恶性肿瘤、长期免疫抑制治疗等已有免疫功能低下状况的人群更容易感染。与2019冠状病毒病(COVID-19)相关的毛霉菌病因其高死亡率而被证明具有灾难性。鼻眶毛霉菌病是最常见的形式。初级保健医生作为首先接触患者且往往(在发展中国家更是如此)也是与医疗专业人员的唯一接触点,在这种疾病的诊断和管理中起着关键作用。降低死亡率的关键是早期发现和诊断,随后采取预防措施以控制病情发展至脑部。各专业的多学科方法是有效诊断和管理的先决条件。抗真菌治疗、手术清创以及切除受影响区域是需要遵循的方案。术后缺损会导致功能、语音和美观方面的损害。这些缺损的修复性康复已显示出良好效果,尤其是在老年人和免疫功能低下的个体中。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/790d/9638618/b4c96e837569/JFMPC-11-4293-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/790d/9638618/33aa6413ade0/JFMPC-11-4293-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/790d/9638618/b4c96e837569/JFMPC-11-4293-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/790d/9638618/33aa6413ade0/JFMPC-11-4293-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/790d/9638618/b4c96e837569/JFMPC-11-4293-g002.jpg

相似文献

1
Diagnosis and management of mucormycosis in the dental clinic: A guide for oral health professionals in India.牙科诊所中毛霉菌病的诊断与管理:印度口腔健康专业人员指南
J Family Med Prim Care. 2022 Aug;11(8):4293-4298. doi: 10.4103/jfmpc.jfmpc_1373_21. Epub 2022 Aug 30.
2
Study of Profile of Mucormycosis During the Second Wave of COVID-19 in a Tertiary Care Hospital.三级护理医院中新冠疫情第二波期间毛霉菌病概况研究
Cureus. 2022 Jan 9;14(1):e21054. doi: 10.7759/cureus.21054. eCollection 2022 Jan.
3
Epidemiology, clinical profile, management, and outcome of COVID-19-associated rhino-orbital-cerebral mucormycosis in 2826 patients in India - Collaborative OPAI-IJO Study on Mucormycosis in COVID-19 (COSMIC), Report 1.印度 2826 例 COVID-19 相关的鼻-眶-脑毛霉菌病的流行病学、临床特征、治疗和结局 - 合作 OPAI-IJO 新冠病毒相关毛霉菌病研究(COSMIC),报告 1。
Indian J Ophthalmol. 2021 Jul;69(7):1670-1692. doi: 10.4103/ijo.IJO_1565_21.
4
Orbital Mucormycosis: Understanding the Deadly Fungus Sweeping the Globe.眼眶毛霉菌病:了解席卷全球的致命真菌。
Cureus. 2023 Jun 26;15(6):e41010. doi: 10.7759/cureus.41010. eCollection 2023 Jun.
5
Rhino-orbital mucormycosis in COVID-19 (Corona Virus Disease): A case report.新型冠状病毒肺炎(COVID-19)合并鼻眶毛霉菌病:一例报告
J Family Med Prim Care. 2022 Jun;11(6):3321-3325. doi: 10.4103/jfmpc.jfmpc_1194_21. Epub 2022 Jun 30.
6
Analog and Digital Protocols for Functional Prosthetic Rehabilitation of Post-COVID-19 Rhino-Orbito Cerebral Mucormycosis Maxillofacial Defects: A Case Series.新冠后鼻眶脑型毛霉菌病颌面缺损功能修复的模拟与数字协议:病例系列
J Pharm Bioallied Sci. 2023 Jul;15(Suppl 2):S1347-S1350. doi: 10.4103/jpbs.jpbs_79_23. Epub 2023 Jul 11.
7
Is mucormycosis the end? A comprehensive management of orbit in COVID associated rhino-orbital-cerebral mucormycosis: preserving the salvageable.是否意味着毛霉菌病的终结?COVID 相关的鼻-眶-脑毛霉菌病的全面管理:保留可挽救的。
Eur Arch Otorhinolaryngol. 2023 Feb;280(2):819-827. doi: 10.1007/s00405-022-07620-3. Epub 2022 Sep 2.
8
Rhino-orbital-cerebral mucormycosis as a complication of coronavirus disease 2019.鼻眶脑型毛霉菌病作为2019冠状病毒病的一种并发症
World J Virol. 2022 Sep 25;11(5):293-299. doi: 10.5501/wjv.v11.i5.293.
9
Mucormycosis, past and present: a comprehensive review.毛霉病:过去与现在——全面综述
Future Microbiol. 2023 Feb;18:217-234. doi: 10.2217/fmb-2022-0141. Epub 2023 Mar 27.
10
Rhino-orbital-cerebral mucormycosis.鼻-眶-脑毛霉病。
Curr Infect Dis Rep. 2012 Aug;14(4):423-34. doi: 10.1007/s11908-012-0272-6.

引用本文的文献

1
Analysis of the clinical parameters and management aspects of rhino-maxillary mucormycosis, Part I: challenges in diagnosis.鼻上颌毛霉菌病的临床参数及管理方面分析,第一部分:诊断挑战
BMC Oral Health. 2025 Jul 31;25(1):1286. doi: 10.1186/s12903-025-05842-5.
2
Green Chemistry and Techniques for Synthesis of Novel Pyranopyrazole and Pyrazolo-pyrano-pyrimidine Derivatives as Promising Antifungal Agents.绿色化学与新型吡喃并吡唑和吡唑并[3,4-d]嘧啶衍生物的合成技术,作为有前途的抗真菌剂。
Recent Adv Antiinfect Drug Discov. 2024;19(3):216-231. doi: 10.2174/0127724344269458231124123935.
3
Oral Manifestations of Mucormycosis: A Systematic Review.

本文引用的文献

1
Pathogenesis and Pathology of COVID-Associated Mucormycosis: What Is New and Why.新型冠状病毒相关毛霉菌病的发病机制与病理学:新进展及原因
Curr Fungal Infect Rep. 2022;16(4):206-220. doi: 10.1007/s12281-022-00443-z. Epub 2022 Sep 29.
2
Identifying Mucormycosis Severity in Indian COVID-19 Patients: A Nano-Based Diagnosis and the Necessity for Critical Therapeutic Intervention.识别印度新冠肺炎患者的毛霉菌病严重程度:基于纳米技术的诊断及关键治疗干预的必要性
Antibiotics (Basel). 2021 Oct 27;10(11):1308. doi: 10.3390/antibiotics10111308.
3
Jalaneti as primary intervention in suspected rhino-orbito-cerebral mucormycosis helps improving the recovery: A case report.
毛霉菌病的口腔表现:一项系统综述
J Fungi (Basel). 2023 Sep 16;9(9):935. doi: 10.3390/jof9090935.
4
Stress Distribution of the Zygomatic Implants in Post-mucormycosis Case: A Finite Element Analysis.毛霉菌病后病例中颧骨种植体的应力分布:有限元分析
J Maxillofac Oral Surg. 2023 Apr 9;22(3):1-7. doi: 10.1007/s12663-023-01914-7.
鼻腔灌洗作为疑似鼻眶脑型毛霉菌病的主要干预措施有助于改善康复:一例报告
J Ayurveda Integr Med. 2022 Apr-Jun;13(2):100516. doi: 10.1016/j.jaim.2021.08.009. Epub 2021 Nov 1.
4
Mucormycosis in COVID-19: A systematic review of cases reported worldwide and in India.COVID-19 相关毛霉菌病:全球及印度病例报告的系统综述。
Diabetes Metab Syndr. 2021 Jul-Aug;15(4):102146. doi: 10.1016/j.dsx.2021.05.019. Epub 2021 May 21.
5
Painful palatal lesion in a patient with COVID-19.一名新冠肺炎患者出现的疼痛性腭部病变。
Oral Surg Oral Med Oral Pathol Oral Radiol. 2021 Jun;131(6):620-625. doi: 10.1016/j.oooo.2021.03.010. Epub 2021 Mar 28.
6
Fungal Infections of Oral Cavity: Diagnosis, Management, and Association with COVID-19.口腔真菌感染:诊断、管理及与2019冠状病毒病的关联
SN Compr Clin Med. 2021;3(6):1373-1384. doi: 10.1007/s42399-021-00873-9. Epub 2021 Mar 27.
7
Coronavirus Disease (Covid-19) Associated Mucormycosis (CAM): Case Report and Systematic Review of Literature.冠状病毒病(新冠-19)相关毛霉菌病(CAM):病例报告及文献系统综述
Mycopathologia. 2021 May;186(2):289-298. doi: 10.1007/s11046-021-00528-2. Epub 2021 Feb 5.
8
Mucormycosis Following Tooth Extraction in a Diabetic Patient: A Case Report.糖尿病患者拔牙后发生毛霉菌病:一例报告
Cureus. 2020 Aug 15;12(8):e9757. doi: 10.7759/cureus.9757.
9
Global guideline for the diagnosis and management of mucormycosis: an initiative of the European Confederation of Medical Mycology in cooperation with the Mycoses Study Group Education and Research Consortium.全球毛霉病诊断和管理指南:欧洲医学真菌学会联合会与真菌感染研究组教育和研究联盟合作开展的一项倡议。
Lancet Infect Dis. 2019 Dec;19(12):e405-e421. doi: 10.1016/S1473-3099(19)30312-3. Epub 2019 Nov 5.
10
Mucor menace in an immunocompetent young male after dental manipulation.一名免疫功能正常的年轻男性在牙科操作后遭遇毛霉威胁。
J Family Med Prim Care. 2019 Feb;8(2):757-759. doi: 10.4103/jfmpc.jfmpc_412_18.