Ebner H, Lassmann G
Arch Dermatol Res (1975). 1977 Dec 12;260(2):103-10. doi: 10.1007/BF00561115.
In 12 patients suffering from generalized Lichen planus (L.p.) the neural periphery of lesions was studied by modern histochemical and electron microscopical methods. In contrast to the investigations published until now on this subject no signs of neural hyperplasia in L.p. could be found. Only some nerves localized in the Lichen planus infiltrate exhibited morphological changes indicating increased neural de- and regeneration in this region. According to the results obtained the nerve changes in L.p. are caused by the typical inflammatory reaction found in this dermatosis. Therefore the neural theory of L.p. cannot be sustained on a histological basis.
对12例泛发性扁平苔藓患者的皮损神经外周进行了现代组织化学和电子显微镜研究。与迄今发表的关于该主题的研究不同,未发现扁平苔藓有神经增生迹象。仅在扁平苔藓浸润灶中的一些神经出现形态学改变,提示该区域神经退变和再生增加。根据所得结果,扁平苔藓的神经改变是由该皮肤病中典型的炎症反应引起的。因此,扁平苔藓的神经理论在组织学基础上无法成立。