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[伴有食管受累的扁平苔藓]

[Lichen planus with esophageal involvement].

作者信息

Valdés F, Caparrini A, Calzada J M

机构信息

Unidad de Dermatología, Hospital da Costa, Burela, Lugo.

出版信息

Actas Dermosifiliogr. 2007 Jun;98(5):361-4.

Abstract

Lichen planus is an inflammatory disease of unknown etiology which may affect the esophagus. Patients with esophageal lichen planus are usually elderly women. The most frequent symptoms are dysphagia and odynophagia. There is usually concomitant oral involvement in cases of esophageal lichen planus. Endoscopic findings include erosions, exudates and stenosis. Systemic steroids are the most effective therapy for these patients. We report a 68-year-old woman with oral, genital and submammary lesions of lichen planus of nine months duration, that referred dysphagia and odynophagia. The endoscopic study revealed white plaques and areas of friable mucosa without stenosis. Histological findings were not conclusive but excluded changes due to fungal or reflux esophagitis. Biopsy of oral and cutaneous lesions showed typical features of lichen planus. Treatment with systemic steroids significantly improved the symptoms.

摘要

扁平苔藓是一种病因不明的炎症性疾病,可累及食管。食管扁平苔藓患者通常为老年女性。最常见的症状是吞咽困难和吞咽痛。食管扁平苔藓病例通常伴有口腔受累。内镜检查结果包括糜烂、渗出物和狭窄。全身用类固醇是这些患者最有效的治疗方法。我们报告一名68岁女性,患有持续9个月的口腔、生殖器和乳房下扁平苔藓病变,伴有吞咽困难和吞咽痛。内镜检查发现白色斑块和黏膜易碎区域,但无狭窄。组织学检查结果不明确,但排除了真菌或反流性食管炎引起的改变。口腔和皮肤病变的活检显示扁平苔藓的典型特征。全身用类固醇治疗显著改善了症状。

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