日本猫免疫缺陷病毒（FIV）感染的全国性最新流行病学调查。
An updated nation-wide epidemiological survey of feline immunodeficiency virus (FIV) infection in Japan.
作者信息
Nakamura Yuki, Nakamura Yuichi, Ura Asami, Hirata Momoko, Sakuma Masato, Sakata Yoshimi, Nishigaki Kazuo, Tsujimoto Hajime, Setoguchi Asuka, Endo Yasuyuki
机构信息
Laboratory of Veterinary Internal Medicine, Faculty of Agriculture, Kagoshima University, Kagoshima, Japan.
出版信息
J Vet Med Sci. 2010 Aug;72(8):1051-6. doi: 10.1292/jvms.09-0574. Epub 2010 Mar 12.
An updated nation-wide epidemiological survey of feline immunodeficiency virus (FIV) infection was conducted in Japan. Blood samples were collected from 1,770 outdoor accessing cats from March to October 2008. Serologically, 410 cats (23.2%) were positive for anti-FIV antibody. Proviral DNA of the FIV env V3-V5 region isolated from 348 cases could be phylogenetically analyzed. The present study disclosed a geographic distribution of four subtypes (A, B, C and D) of FIV in Japan. Even though an FIV vaccine was introduced in Japan, we do not currently know whether this vaccine is effective against all strains of FIV in Japan or not. Therefore, close attention still has to be paid to epidemic and genotypic trends of FIV.
日本开展了一项关于猫免疫缺陷病毒（FIV）感染的全国性最新流行病学调查。2008年3月至10月期间，从1770只户外接触猫采集了血样。血清学检测显示，410只猫（23.2%）抗FIV抗体呈阳性。对从348例病例中分离出的FIV env V3 - V5区域的前病毒DNA进行了系统发育分析。本研究揭示了日本FIV四种亚型（A、B、C和D）的地理分布。尽管日本已引入FIV疫苗，但目前我们尚不清楚该疫苗是否对日本所有FIV毒株都有效。因此，仍需密切关注FIV的流行和基因型趋势。
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