日本家猫中γ疱疹病毒的分子流行病学研究。
Molecular epidemiological study of gammaherpesvirus in domestic cats in Japan.
作者信息
Tateno Morihiro, Takahashi Masashi, Miyake Eri, Nishigaki Kazuo, Tsujimoto Hajime, Endo Yasuyuki
机构信息
Laboratory of Small Animal Internal Medicine, Joint Faculty of Veterinary Medicine, Kagoshima University, 1-21-24 Korimoto, Kagoshima, Kagoshima 890-0065, Japan.
Laboratory of Molecular Immunology and Infectious Disease, Joint Faculty of Veterinary Medicine, Yamaguchi University, 1677-1 Yoshida, Yamaguchi, Yamaguchi 753-8515, Japan.
出版信息
J Vet Med Sci. 2017 Oct 20;79(10):1735-1740. doi: 10.1292/jvms.17-0039. Epub 2017 Aug 28.
Gammaherpesviruses (GHVs) are members of an emerging subfamily of the family Herpesviridae. A recent study identified a novel GHV in domestic cats (Felis catus GHV1, FcaGHV1), and epidemiological surveys have found that FcaGHV1 is distributed worldwide. In this study, we investigated the prevalence of GHVs in domestic cats in Japan with a molecular epidemiological survey. Blood samples were collected from 1,738 domestic cats and GHV-derived DNA was detected with PCR in 1.3% (23/1,738) of the Japanese domestic cats. The FcaGHV1 detected in this study was very similar to FcaGHV1 detected in a domestic cat in North America. Older age (>5 years old) and Feline immunodeficiency virus infection were identified as risk factors for GHV infection.
γ疱疹病毒（GHV）是疱疹病毒科一个新兴亚科的成员。最近一项研究在家猫中鉴定出一种新型GHV（猫GHV1，FcaGHV1），并且流行病学调查发现FcaGHV1在全球范围内均有分布。在本研究中，我们通过分子流行病学调查研究了日本家猫中GHV的流行情况。从1738只家猫采集血液样本，通过聚合酶链反应（PCR）在1.3%（23/1738）的日本家猫中检测到了GHV衍生的DNA。本研究中检测到的FcaGHV1与在北美一只家猫中检测到的FcaGHV1非常相似。年龄较大（>5岁）和感染猫免疫缺陷病毒被确定为GHV感染的风险因素。
Zotero 插件