Wiese C H R, Bartels U E, Orso S, Graf B M
Klinik für Anästhesiologie, Universitätsklinikum Regensburg, Franz-Josef-Strauss-Allee 11, 93053 Regensburg.
Anaesthesist. 2010 Apr;59(4):333-41. doi: 10.1007/s00101-010-1709-7.
In the medical literature the Lazarus phenomenon is defined as the spontaneous return of circulation (SROC) after cessation of cardio-pulmonary resuscitation. Based on published literature recommendations concerning the treatment of patients after cessation of resuscitation and reasons for the Lazarus phenomenon are discussed.
A literature search in Medline, PubMed, Embase, Google Scholar and Google from 1982 to 2009 was carried out for the terms "Lazarus phenomenon", "cessation of cardiopulmonary resuscitation and return of spontaneous circulation (ROSC)", "spontaneous return of circulation (SROC)", "resuscitation and spontaneous defibrillation", "spontaneous recovery and cardiopulmonary resuscitation". Related secondary literature which was cited in the relevant articles was included as well as publications found in our personal literature base.
More than 10,000 articles and comments could be recovered and of these 45 were considered to be medically relevant articles (letters to the Editor, abstracts, case reports and literature reviews).
In the relevant medical literature, the Lazarus phenomenon is a rare occurrence. It seems to be a phenomenon which has often been described in non-medical literature but not published in medical literature. The pathophysiological mechanisms are poorly understood. In the literature several mechanisms are discussed which could be important for this phenomenon, e.g. autopositive end-expiratory pressure, hyperventilation and alkalosis, hyperkalemia, delayed action of drugs and unobserved minimal vital signs. In the literature it is recommended that patients should be passively monitored for at least 10 min after cessation of resuscitation. However, more scientific experimental investigations seem to be necessary to gain a better understanding of this phenomenon.
在医学文献中，拉撒路现象被定义为心肺复苏停止后循环的自发恢复（SROC）。基于已发表的文献，讨论了关于复苏停止后患者治疗的建议以及拉撒路现象的原因。
在1982年至2009年期间，在Medline、PubMed、Embase、谷歌学术和谷歌上搜索了“拉撒路现象”“心肺复苏停止与自主循环恢复（ROSC）”“循环的自发恢复（SROC）”“复苏与自发除颤”“自发恢复与心肺复苏”等术语。相关文章中引用的相关二次文献以及我们个人文献库中找到的出版物也被纳入。
可检索到10000多篇文章和评论，其中45篇被认为是医学相关文章（给编辑的信、摘要、病例报告和文献综述）。
在相关医学文献中，拉撒路现象很少见。它似乎是一种在非医学文献中经常被描述但未在医学文献中发表的现象。其病理生理机制了解甚少。文献中讨论了几种可能对该现象很重要的机制，例如自动呼气末正压、过度通气和碱中毒、高钾血症、药物延迟作用以及未观察到的最低生命体征。文献中建议在复苏停止后应对患者进行至少10分钟的被动监测。然而，似乎需要更多科学的实验研究来更好地理解这一现象。
