Wang X, Meng M Q-H
Department of Electronic Engineering, The Chinese University of Hong Kong, Hong Kong, People's Republic of China.
Proc Inst Mech Eng H. 2010;224(1):107-18. doi: 10.1243/09544119JEIM540.
Use of the capsule endoscope (CE) in clinical examinations is limited by its passive movement resulting from the natural peristalsis of the gastrointestinal (GI) tract. Therefore, a locomotion mechanism is desirable for the next generation of capsule endoscope. Understanding the resistant properties of the small intestine is essential for designing a wireless magnetic actuation mechanism. In this paper, in vitro experiments were carried out to investigate the resistant force of the small intestine using 15 specially designed capsule prototypes and analysed the effect of the capsule dimension and moving speed. Segments of porcine small intestine were employed as a conservative model for the human intestine. When the capsules under experiment were moving at a speed of 0.5 mm/s, a resistant force of 20 to 100 mN were measured for the capsule diameter in the range of 8 to 13 mm. The force increased with moving speed. The intrinsic cause of the resistant force of the small intestine is discussed based on an analysis of the experimental data. It is believed that the viscoelastic properties of the tissue play an important role in the resistant characteristics of the small intestine.
胶囊内窥镜(CE)在临床检查中的应用受到胃肠道自然蠕动导致的被动运动的限制。因此,下一代胶囊内窥镜需要一种运动机制。了解小肠的阻力特性对于设计无线磁驱动机制至关重要。本文利用15个专门设计的胶囊原型进行了体外实验,以研究小肠的阻力,并分析了胶囊尺寸和移动速度的影响。猪小肠段被用作人类肠道的保守模型。当实验中的胶囊以0.5毫米/秒的速度移动时,对于直径在8至13毫米范围内的胶囊,测得的阻力为20至100毫牛。阻力随移动速度增加。在对实验数据进行分析的基础上,讨论了小肠阻力的内在原因。据信,组织的粘弹性特性在小肠的阻力特性中起着重要作用。