Slawinski Piotr R, Obstein Keith L, Valdastri Pietro
Piotr R Slawinski, Keith L Obstein, Pietro Valdastri, STORM Lab, Department of Mechanical Engineering, Vanderbilt University, Nashville, TN 37212, United States.
World J Gastroenterol. 2015 Oct 7;21(37):10528-41. doi: 10.3748/wjg.v21.i37.10528.
Capsule endoscopes have evolved from passively moving diagnostic devices to actively moving systems with potential therapeutic capability. In this review, we will discuss the state of the art, define the current shortcomings of capsule endoscopy, and address research areas that aim to overcome said shortcomings. Developments in capsule mobility schemes are emphasized in this text, with magnetic actuation being the most promising endeavor. Research groups are working to integrate sensor data and fuse it with robotic control to outperform today's standard invasive procedures, but in a less intrusive manner. With recent advances in areas such as mobility, drug delivery, and therapeutics, we foresee a translation of interventional capsule technology from the bench-top to the clinical setting within the next 10 years.
胶囊内镜已从被动移动的诊断设备发展成为具有潜在治疗能力的主动移动系统。在本综述中,我们将讨论其当前的技术水平,明确胶囊内镜目前存在的不足,并探讨旨在克服这些不足的研究领域。本文重点强调了胶囊移动方案的发展,其中磁驱动是最具前景的方向。研究团队正在努力整合传感器数据,并将其与机器人控制相结合,以超越当今标准的侵入性手术,同时保持较低的侵入性。随着在移动性、药物递送和治疗等领域的最新进展,我们预计在未来10年内,介入性胶囊技术将从实验室走向临床应用。