Slawinski Piotr R, Oleynikov Dmitry, Terry Benjamin S
Department of Mechanical and Materials Engineering, University of Nebraska-Lincoln, Nebraska Hall , Lincoln , USA and.
J Med Eng Technol. 2015 Jan;39(1):54-9. doi: 10.3109/03091902.2014.973619. Epub 2014 Nov 4.
This work describes the development and validation of a novel device which simulates important forces experienced by Robotic Capsule Endoscopes (RCE) in vivo in the small intestine. The purpose of the device is to expedite and lower the cost of RCE development. Currently, there is no accurate in vitro test method nor apparatus to validate new RCE designs; therefore, RCEs are tested in vivo at a cost of ∼$1400 per swine test. The authors have developed an in vitro RCE testing device which generates two peristaltic waves to accurately simulate the two biomechanical actions of the human small intestine that are most relevant to RCE locomotion: traction force and contact force. The device was successfully calibrated to match human physiological ranges for traction force (4-40 gf), contact force (80-500 gf) and peristaltic wave propagation speed (0.08-2 cm s(-1)) for a common RCE capsule geometry of 3.5 cm length and 1.5 cm diameter.
这项工作描述了一种新型设备的开发与验证,该设备可模拟机器人胶囊内窥镜(RCE)在体内小肠中所经历的重要力。该设备的目的是加快RCE的开发并降低成本。目前,尚无准确的体外测试方法或仪器来验证新的RCE设计;因此,RCE在体内进行测试,每次猪测试的成本约为1400美元。作者开发了一种体外RCE测试设备,该设备可产生两个蠕动波,以准确模拟人类小肠与RCE运动最相关的两种生物力学作用:牵引力和接触力。对于长度为3.5 cm、直径为1.5 cm的常见RCE胶囊几何形状,该设备已成功校准,以匹配人类生理范围内的牵引力(4 - 40 gf)、接触力(80 - 500 gf)和蠕动波传播速度(0.08 - 2 cm s⁻¹)。