Sánchez-Sánchez R, Rodríguez-Fernández A, Ramírez-Navarro A, Gómez-Río M, Ramos-Font C, Llamas-Elvira J M
Servicio de Medicina Nuclear, Hospital Universitario Virgen de las Nieves, Granada, España.
Rev Esp Med Nucl. 2010 May-Jun;29(3):131-4. doi: 10.1016/j.remn.2010.01.002. Epub 2010 Mar 15.
The combination of positron emission tomography (PET) and computed tomography (CT) in a single device (PET/CT) offers a powerful diagnostic tool that opens up new horizons for imaging diagnosis. In order to correctly interpret PET/CT studies, knowledge of the biodistribution of 18F-fluorodeoxyglucose (FDG), the physiological variants as well as the pitfalls, including artefacts, which may be found, is necessary. We report four cases performed during the follow-up diagnostic context of an oncology study performed with 18F-FDG-PET/CT. In every case, this study showed focal uptake in the lung parenchyma in the PET study with no structural lesions being found on the CT scan. Radiotracer extravasation in three of these patients and a recent change in the injection protocol used suggest that an artefact was responsible for these discrepancies.
正电子发射断层扫描（PET）与计算机断层扫描（CT）整合于一台设备（PET/CT），提供了一种强大的诊断工具，为影像诊断开辟了新视野。为正确解读PET/CT检查结果，有必要了解18F-氟脱氧葡萄糖（FDG）的生物分布、生理变异以及可能出现的陷阱，包括伪影。我们报告了4例在一项使用18F-FDG-PET/CT进行的肿瘤学研究随访诊断过程中进行的病例。在每例病例中，PET检查显示肺实质有局灶性摄取，而CT扫描未发现结构病变。其中3例患者存在放射性示踪剂外渗，且最近使用的注射方案有所改变，提示这些差异是由伪影导致的。
