Hot-clot artifact in the lung parenchyma on F-fluorodeoxyglucose positron emission tomography/computed tomography mimicking malignancy with a homolateral non-small cell lung cancer.

F-fluorodeoxyglucose (F-FDG) positron emission tomography/computed tomography (CT) is an important tool widely used in the oncology to stage and restage various malignancies. Intense focal FDG uptake in the lung parenchyma associated with the absence of anatomical lesion detected on CT can be explained by a lung microembolism, known as hot-clot artifact. We report, to the best of our knowledge, the first case describing a single hot-clot artifact located in the same lung as a histologically proven non-small cell lung cancer.