Clinical Microbiology and Public Health Laboratory, Health Protection Agency, Addenbrooke's Hospital, Hills Road, Cambridge CB2 0QW, UK.
J Clin Virol. 2010 May;48(1):58-61. doi: 10.1016/j.jcv.2010.02.004. Epub 2010 Mar 15.
This report describes a case of severe hepatitis in an individual returning from India which was found to be the result of infection with HEV genotype 4. HEV was diagnosed using a novel RT-PCR assay (with internal control) for HEV RNA detection/quantitation, described herein. This is the first documented report of zoonotic transmission of HEV genotype 4 infection acquired in India.
本报告描述了一例从印度返回的个体发生严重肝炎的病例,该病例被发现是感染了 HEV 基因型 4 的结果。使用本文所述的新型 RT-PCR 检测方法(带内部对照)检测和定量 HEV RNA 来诊断 HEV。这是在印度获得的 HEV 基因型 4 感染的动物源性传播的首例有记录报告。