Department of Dermatology and STD, Jawaharlal Institute of Postgraduate Medical Education and Research, Pondicherry-605 006, India.
Indian J Dermatol Venereol Leprol. 2010 Mar-Apr;76(2):103-15. doi: 10.4103/0378-6323.60540.
Diet has an important role to play in many skin disorders, and dermatologists are frequently faced with the difficulty of separating myth from fact when it comes to dietary advice for their patients. Patients in India are often anxious about what foods to consume, and what to avoid, in the hope that, no matter how impractical or difficult this may be, following this dictum will cure their disease. There are certain disorders where one or more components in food are central to the pathogenesis, e.g. dermatitis herpetiformis, wherein dietary restrictions constitute the cornerstone of treatment. A brief list, although not comprehensive, of other disorders where diet may have a role to play includes atopic dermatitis, acne vulgaris, psoriasis vulgaris, pemphigus, urticaria, pruritus, allergic contact dermatitis, fish odor syndrome, toxic oil syndrome, fixed drug eruption, genetic and metabolic disorders (phenylketonuria, tyrosinemia, homocystinuria, galactosemia, Refsum's disease, G6PD deficiency, xanthomas, gout and porphyria), nutritional deficiency disorders (kwashiorkar, marasmus, phrynoderma, pellagra, scurvy, acrodermatitis enteropathica, carotenemia and lycopenemia) and miscellaneous disorders such as vitiligo, aphthous ulcers, cutaneous vasculitis and telogen effluvium. From a practical point of view, it will be useful for the dermatologist to keep some dietary information handy to deal with the occasional patient who does not seem to respond in spite of the best, scientific and evidence-based therapy.
饮食在许多皮肤疾病中起着重要作用,皮肤科医生在为患者提供饮食建议时,经常面临将神话与事实区分开来的困难。印度的患者常常对应该吃什么食物、避免吃什么食物感到焦虑,他们希望无论这多么不切实际或困难,遵循这一原则就能治愈他们的疾病。在某些疾病中,食物中的一个或多个成分是发病机制的核心,例如疱疹样皮炎,其中饮食限制构成治疗的基石。尽管不全面,但饮食可能在其他一些疾病中发挥作用的简要列表包括特应性皮炎、寻常痤疮、银屑病、天疱疮、荨麻疹、瘙痒、过敏性接触性皮炎、鱼腥综合征、毒油综合征、固定性药物疹、遗传和代谢疾病(苯丙酮尿症、酪氨酸血症、同型胱氨酸尿症、半乳糖血症、Refsum 病、G6PD 缺乏症、黄瘤病、痛风和卟啉病)、营养缺乏症(夸希奥科病、消瘦症、糙皮病、糙皮病、坏血病、肠病性肢端皮炎、胡萝卜血症和番茄红素血症)和各种疾病,如白癜风、口腔溃疡、皮肤血管炎和休止期脱发。从实际的角度来看,皮肤科医生掌握一些饮食信息将有助于处理偶尔出现的患者,尽管采用了最佳的科学和循证治疗,但这些患者似乎仍未得到缓解。