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Failure of the stem cell niche rather than loss of oocyte stem cells in the aging ovary.

作者信息

Massasa Efi, Costa Xavier Santamaria, Taylor Hugh S

机构信息

Yale University School of Medicine, New Haven, CT 06510, USA.

出版信息

Aging (Albany NY). 2010 Jan 26;2(1):1-2. doi: 10.18632/aging.100119.

DOI:10.18632/aging.100119
PMID:20228937
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2837200/
Abstract
摘要

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Failure of the stem cell niche rather than loss of oocyte stem cells in the aging ovary.衰老卵巢中是干细胞微环境的衰竭而非卵母细胞干细胞的缺失。
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Stem cells in aged mammalian ovaries.衰老哺乳动物卵巢中的干细胞
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Effects of low-intensity pulsed ultrasound (LIPUS)-pretreated human amnion-derived mesenchymal stem cell (hAD-MSC) transplantation on primary ovarian insufficiency in rats.低强度脉冲超声(LIPUS)预处理的人羊膜间充质干细胞(hAD-MSC)移植对大鼠原发性卵巢功能不全的影响。
Stem Cell Res Ther. 2017 Dec 19;8(1):283. doi: 10.1186/s13287-017-0739-3.

本文引用的文献

1
Aged mouse ovaries possess rare premeiotic germ cells that can generate oocytes following transplantation into a young host environment.老年小鼠的卵巢含有罕见的减数分裂前生殖细胞,将其移植到年轻宿主环境中后能够产生卵母细胞。
Aging (Albany NY). 2009 Dec 12;1(12):971-8. doi: 10.18632/aging.100105.
2
Production of offspring from a germline stem cell line derived from neonatal ovaries.源自新生卵巢的生殖系干细胞系产生后代。
Nat Cell Biol. 2009 May;11(5):631-6. doi: 10.1038/ncb1869. Epub 2009 Apr 12.
3
Bone marrow transplantation generates immature oocytes and rescues long-term fertility in a preclinical mouse model of chemotherapy-induced premature ovarian failure.在化疗诱导的卵巢早衰临床前小鼠模型中,骨髓移植可产生未成熟卵母细胞并挽救长期生育能力。
J Clin Oncol. 2007 Aug 1;25(22):3198-204. doi: 10.1200/JCO.2006.10.3028.
4
Ovulated oocytes in adult mice derive from non-circulating germ cells.成年小鼠排出的卵母细胞来源于非循环的生殖细胞。
Nature. 2006 Jun 29;441(7097):1109-14. doi: 10.1038/nature04929. Epub 2006 Jun 14.
5
Oocyte generation in adult mammalian ovaries by putative germ cells in bone marrow and peripheral blood.成年哺乳动物卵巢中由骨髓和外周血中的假定生殖细胞产生卵母细胞。
Cell. 2005 Jul 29;122(2):303-15. doi: 10.1016/j.cell.2005.06.031.
6
Germline stem cells and follicular renewal in the postnatal mammalian ovary.出生后哺乳动物卵巢中的生殖系干细胞与卵泡更新
Nature. 2004 Mar 11;428(6979):145-50. doi: 10.1038/nature02316.