Brateman L, Buckley K, Keim S G, Wargovich T J, Williams C M
Department of Radiology, Veterans Administration Medical Center, Gainesville, FL 32602.
J Nucl Med. 1991 May;32(5):777-82.
Radionuclide ventriculography and contrast ventriculography were performed in two comparable projections on 50 patients with suspected coronary artery disease. The efficacy of conventional cine display and Fourier image analysis of the radionuclide ventriculogram was compared using contrast ventriculography as the gold standard. Of seven different combinations of Fourier images, the combination of left anterior oblique amplitude and phase and left posterior oblique amplitude and phase provided the highest sensitivity (87%), specificity (83%), accuracy (86%), and kappa coefficient (0.64). To increase statistical power, segment data were collapsed to global data in which a heart was considered normal if all segments were normal and abnormal if one or more segments were abnormal. Fourier images had higher sensitivity (Fourier 87%, cine 47%); lower specificity (Fourier 83%, cine 92%), higher accuracy (Fourier 86%, cine 58%), and higher kappa coefficient (Fourier 0.64, cine 0.25), and these differences were statistically significant (p less than 0.01).
对50例疑似冠心病患者在两个可比投照位上进行了放射性核素心室造影和对比心室造影。以对比心室造影作为金标准，比较了放射性核素心室造影的传统电影显示和傅里叶图像分析的效能。在七种不同的傅里叶图像组合中，左前斜位振幅和相位与左后斜位振幅和相位的组合提供了最高的灵敏度（87%）、特异性（83%）、准确性（86%）和kappa系数（0.64）。为了提高统计效能，将节段数据合并为整体数据，即如果所有节段正常，则心脏被视为正常；如果一个或多个节段异常，则心脏被视为异常。傅里叶图像具有更高的灵敏度（傅里叶87%，电影47%）；更低的特异性（傅里叶83%，电影92%），更高的准确性（傅里叶86%，电影58%）和更高的kappa系数（傅里叶0.64，电影0.25），并且这些差异具有统计学意义（p小于0.01）。
