Case Western Reserve University.
Neuropsychology. 2010 Mar;24(2):148-59. doi: 10.1037/a0018112.
To investigate postconcussive symptoms (PCS) following pediatric mild traumatic brain injury (mTBI), 8- to 15-year-old children with mTBI (n = 186) and a comparison group with uncomplicated orthopedic injuries (OI, n = 99) were recruited from two emergency departments. Parent and child ratings of PCS and symptom counts were obtained within 3 weeks after injury (baseline) and at 1, 3, and 12 months postinjury. The mTBI group also completed magnetic resonance imaging at baseline. Group differences were examined using growth modeling, controlling for age at injury, sex, socioeconomic status, and (for parent-based measures) preinjury symptom levels. Relative to the OI group, the mTBI group had higher ratings of somatic PCS and parent counts of PCS at the initial assessments, but higher parent ratings of cognitive PCS and child counts of PCS throughout follow-up. Higher levels of PCS in the mTBI group were associated with motor-vehicle-related trauma, loss of consciousness, neuroimaging abnormalities, and hospitalization. The findings validate both transient and persistent PCS in children with mTBI and document associations of symptoms with injury and noninjury factors.
为了调查儿科轻度创伤性脑损伤（mTBI）后的脑震荡后症状（PCS），我们从两家急诊室招募了 186 名 mTBI 患儿（n=186）和 99 名无并发症骨科损伤（OI）的对照组患儿。在损伤后 3 周内（基线）和 1、3 和 12 个月时，家长和孩子对 PCS 和症状计数进行了评分。mTBI 组还在基线时进行了磁共振成像。使用增长模型，控制损伤时的年龄、性别、社会经济地位以及（对于基于家长的措施）受伤前的症状水平，对组间差异进行了检验。与 OI 组相比，mTBI 组在初始评估时的躯体 PCS 评分和家长报告的 PCS 计数更高，但在整个随访过程中，父母对认知 PCS 和儿童 PCS 计数的评分更高。mTBI 组中更高水平的 PCS 与与机动车相关的创伤、意识丧失、神经影像学异常和住院有关。这些发现验证了 mTBI 儿童存在短暂和持续的 PCS，并记录了症状与损伤和非损伤因素的关联。
