Department of Physical Medicine and Rehabilitation,Wisconsin, Milwaukee, Wisconsin, USA.
Pain Pract. 2010 Sep-Oct;10(5):485-91. doi: 10.1111/j.1533-2500.2009.00353.x.
Residual limb pain (RLP) and phantom limb pain (PLP) can be debilitating and can prevent functional gains following amputation. High correlations have been reported between RLP and the stump neuromas following amputation. Many treatment methods including physical therapy, medications, and interventions, have been used with limited success. Pulsed radiofrequency ablation (PRFA) has shown promise in treating neuropathic pain because of the inhibition of evoked synaptic activity. We present 4 amputees who were treated with PRFA after failing conservative management for their RLP and PLP. All 4 patients underwent PRFA and demonstrated at least 80% relief of RLP for over 6 months. One patient reported a complete resolution of phantom sensation while another patient had significantly decreased frequency of spontaneous PLP and resolution of evoked PLP. In addition, all patients reported improved overall function including increased prosthetic tolerance and decreased oral pain medications. This case series suggests that PRFA is a viable treatment option which might be used for long-term relief of intractable RLP and/or PLP.
残肢痛(RLP)和幻肢痛(PLP)可能使人衰弱,并可能妨碍截肢后的功能恢复。截肢后残肢神经瘤与 RLP 之间存在高度相关性。许多治疗方法,包括物理疗法、药物和干预措施,都取得了有限的成功。脉冲射频消融(PRFA)因其抑制诱发电位突触活动而在治疗神经病理性疼痛方面显示出前景。我们介绍了 4 名接受 PRFA 治疗的截肢患者,他们在保守治疗 RLP 和 PLP 失败后接受了 PRFA 治疗。所有 4 名患者均接受了 PRFA 治疗,RLP 缓解至少 80%,持续超过 6 个月。1 名患者报告幻肢感觉完全消失,另 1 名患者自发性 PLP 发作频率显著降低,诱发性 PLP 消失。此外,所有患者报告整体功能改善,包括增加对假肢的耐受性和减少口服止痛药的使用。该病例系列表明,PRFA 是一种可行的治疗选择,可用于长期缓解难治性 RLP 和/或 PLP。