Department of Anesthesia, Critical Care, and Pain Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.
Pain Physician. 2011 Jul-Aug;14(4):371-6.
Chronic lumbosacral radicular pain is a common source of radiating leg pain seen in pain management patients. These patients are frequently managed conservatively with multiple modalities including medications, physical therapy, and epidural steroid injections. Radiofrequency has been used to treat chronic radicular pain for over 30 years; however, there is a paucity of literature about the safety and efficacy of repeat radiofrequency lesioning.
To determine the safety, success rate, and duration of pain relief of repeat pulsed radiofrequency (PRF) and continuous radiofrequency (CRF) lesioning of the dorsal root ganglion (DRG)/ sacral segmental nerves (SN) in patients with chronic lumbosacral radicular pain.
Retrospective chart review
Outpatient multidisciplinary pain center
Medical record review of patients who were treated with pulsed and continuous radiofrequency lesioning of the lumbar dorsal root ganglia and segmental nerves and who reported initial success were evaluated for recurrence of pain and repeat radiofrequency treatment. Responses to subsequent treatments were compared to initial treatments for success rates, average duration of relief, and adverse neurologic side-effects.
Retrospective chart review without a control group.
Twenty-six women and 24 men were identified who received 50% pain relief or better after PRF and CRF of the lumbar DRG/ sacral SN for lumbosacral radicular pain. The mean age was 62 years (range, 25-86). The mean duration of relief for the 40 patients who had 2 treatments was 4.7 months (range 0-24; Se [standard error] 0.74). Twenty-eight patients had 3 treatments with an average duration of relief of 4.5 months (range 0-19 months; Se 0.74). Twenty patients had 4 treatments with a mean duration of relief of 4.4 months (range 0.5-18; Se 0.95) and 18 patients who had 5 or more treatments received an average duration of relief of 4.3 months (range 0.5-18; Se 1.03). The average duration of relief and success frequency remained constant after each subsequent radiofrequency treatment. Of the 50 total patients, there was only 1 reported complication, specifically, transient thigh numbness which resolved after one week.
Repeated pulsed and continuous radiofrequency ablation of the lumbar dorsal root ganglion/segmental nerve shows promise to be a safe and effective long-term palliative management for lumbosacral radicular pain in some patients.
慢性腰骶神经根痛是疼痛管理患者中常见的放射状腿部疼痛源。这些患者经常通过多种方式进行保守治疗,包括药物、物理治疗和硬膜外类固醇注射。射频已用于治疗慢性根性疼痛超过 30 年;然而,关于重复射频消融的安全性和疗效的文献很少。
确定重复脉冲射频 (PRF) 和连续射频 (CRF) 消融腰骶神经根 (DRG)/骶段神经 (SN) 治疗慢性腰骶神经根痛患者的安全性、成功率和疼痛缓解持续时间。
回顾性图表审查
门诊多学科疼痛中心
对接受脉冲和连续射频消融腰骶部 DRG 和节段神经并报告初始成功的患者的病历进行回顾性评估,以评估疼痛复发和重复射频治疗。将随后治疗的反应与初始治疗的成功率、平均缓解持续时间和不良神经副作用进行比较。
没有对照组的回顾性图表审查。
确定了 26 名女性和 24 名男性,他们在接受 PRF 和 CRF 治疗后,腰骶部 DRG/骶 SN 的疼痛缓解率达到 50%或以上,用于治疗腰骶神经根痛。平均年龄为 62 岁(范围 25-86 岁)。40 名接受 2 次治疗的患者的平均缓解持续时间为 4.7 个月(范围 0-24;Se[标准误差]0.74)。28 名患者接受了 3 次治疗,平均缓解持续时间为 4.5 个月(范围 0-19 个月;Se0.74)。20 名患者接受了 4 次治疗,平均缓解持续时间为 4.4 个月(范围 0.5-18;Se0.95),18 名接受了 5 次或更多治疗的患者平均缓解持续时间为 4.3 个月(范围 0.5-18;Se1.03)。每次后续射频治疗后,缓解持续时间和成功率均保持不变。在 50 名总患者中,只有 1 例报告并发症,即短暂大腿麻木,一周后缓解。
重复脉冲和连续射频消融腰骶部背根神经节/节段神经有望成为一些患者腰骶神经根痛的安全有效长期姑息治疗方法。