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肯尼亚母婴安全项目:产前检查、服务提供情况评估及其对 PMTCT 的影响。

A Safe Motherhood project in Kenya: assessment of antenatal attendance, service provision and implications for PMTCT.

机构信息

International Centre for Reproductive Health, Department of Obstetrics and Gynaecology, Ghent University, Ghent, Belgium.

出版信息

Trop Med Int Health. 2010 May;15(5):584-91. doi: 10.1111/j.1365-3156.2010.02499.x. Epub 2010 Mar 10.

Abstract

OBJECTIVES

To investigate uptake and provision of antenatal care (ANC) services in the Uzazi Bora project: a demonstration-intervention project for Safe Motherhood and prevention of mother-to-child transmission of HIV in Kenya.

METHODS

Data were extracted from antenatal clinic, laboratory and maternity ward registers of all pregnant women attending ANC from January 2004 until September 2006 at three antenatal clinics in Mombasa and two in rural Kwale district of Coast Province, Kenya (n = 25 364). Multiple logistic and proportional odds logistic regression analyses assessed changes over time, and determinants of the frequency and timing of ANC visits, uptake of HIV testing, and provision of iron sulphate, folate and single-dose nevirapine (sd-NVP).

RESULTS

About half of women in rural and urban settings (52.2% and 49.2%, respectively) attended antenatal clinics only once. Lower parity, urban setting, older age and having received iron sulphate and folate supplements during the first ANC visit were independent predictors of more frequent visits. The first ANC visit occurred after 28 weeks of pregnancy for 30% (5894/19 432) of women. By mid-2006, provision of nevirapine to HIV-positive women had increased from 32.5% and 11.7% in rural and urban clinics, to 67.0% and 74.6%, respectively. Equally marked improvements were observed in the uptake of HIV testing and the provision of iron sulphate and folate.

CONCLUSION

Provision of ANC services, including sd-NVP, increased markedly over time. While further improvements in quality are necessary, particular attention is needed to implement evidence-based interventions to alter ANC utilization patterns. Encouragingly, improved provision of basic essential obstetric care may increase attendance.

摘要

目的

调查乌扎齐博拉项目中产前护理(ANC)服务的利用情况和提供情况:肯尼亚安全孕产和预防母婴传播艾滋病毒的示范干预项目。

方法

从 2004 年 1 月至 2006 年 9 月,在肯尼亚滨海省蒙巴萨的三个产前诊所和两个农村夸莱区的两个产前诊所,从参加 ANC 的所有孕妇的产前诊所、实验室和产科病房登记册中提取数据(n=25364)。多元逻辑和比例优势逻辑回归分析评估了随时间的变化以及 ANC 就诊频率和时间、艾滋病毒检测的采用、以及铁硫酸、叶酸和单剂量奈韦拉平(sd-NVP)的提供情况的决定因素。

结果

农村和城市环境中约有一半的妇女(分别为 52.2%和 49.2%)仅参加过一次产前诊所。较低的生育次数、城市环境、年龄较大以及在第一次 ANC 就诊时接受铁硫酸和叶酸补充剂是更频繁就诊的独立预测因素。30%(5894/19432)的妇女在妊娠 28 周后首次进行 ANC 就诊。到 2006 年年中,向艾滋病毒阳性妇女提供奈韦拉平的比例从农村和城市诊所的 32.5%和 11.7%分别增加到 67.0%和 74.6%。艾滋病毒检测的采用以及铁硫酸和叶酸的提供也同样有明显的改善。

结论

ANC 服务的提供,包括 sd-NVP,随时间有明显增加。虽然需要进一步提高质量,但特别需要注意实施基于证据的干预措施,以改变 ANC 的利用模式。令人鼓舞的是,基本产科保健的改善可能会增加就诊率。

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