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1
Mammalian target of rapamycin (mTOR): conducting the cellular signaling symphony.
J Biol Chem. 2010 May 7;285(19):14071-7. doi: 10.1074/jbc.R109.094003. Epub 2010 Mar 15.
2
mTOR signaling: at the crossroads of plasticity, memory and disease.
Trends Neurosci. 2010 Feb;33(2):67-75. doi: 10.1016/j.tins.2009.11.003. Epub 2009 Dec 4.
3
mTOR signaling in autophagy regulation in the kidney.
Semin Nephrol. 2014 Jan;34(1):2-8. doi: 10.1016/j.semnephrol.2013.11.002. Epub 2013 Nov 21.
4
mTOR signaling in cancer cell motility and tumor metastasis.
Crit Rev Eukaryot Gene Expr. 2010;20(1):1-16. doi: 10.1615/critreveukargeneexpr.v20.i1.10.
6
MTOR downregulates iodide uptake in thyrocytes.
J Endocrinol. 2010 Jul;206(1):113-20. doi: 10.1677/JOE-09-0436. Epub 2010 Apr 14.
7
Targeting mTOR globally in cancer: thinking beyond rapamycin.
Cell Cycle. 2009 Dec;8(23):3831-7. doi: 10.4161/cc.8.23.10070. Epub 2009 Dec 14.
8
The mammalian target of rapamycin: linking T cell differentiation, function, and metabolism.
Immunity. 2010 Sep 24;33(3):301-11. doi: 10.1016/j.immuni.2010.09.002.
9
Common corruption of the mTOR signaling network in human tumors.
Oncogene. 2008 Dec;27 Suppl 2(0 2):S43-51. doi: 10.1038/onc.2009.352.
10
The multifunctional role of mTOR in innate immunity: implications for transplant immunity.
Am J Transplant. 2009 Dec;9(12):2655-61. doi: 10.1111/j.1600-6143.2009.02832.x. Epub 2009 Sep 25.

引用本文的文献

1
Exploring the role of mTOR pathway in aging and age-related disorders.
EXCLI J. 2025 Aug 4;24:992-1015. doi: 10.17179/excli2025-8384. eCollection 2025.
2
Rapamycin rescues APC-mutated colon organoid differentiation.
Cancer Gene Ther. 2025 Jul 23. doi: 10.1038/s41417-025-00935-3.
4
Research progress of cPLA2 in cardiovascular diseases (Review).
Mol Med Rep. 2025 Apr;31(4). doi: 10.3892/mmr.2025.13468. Epub 2025 Feb 21.
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Cerebral Cavernous Malformation: From Genetics to Pharmacotherapy.
Brain Behav. 2025 Jan;15(1):e70223. doi: 10.1002/brb3.70223.
6
PEGylated iron oxide-gold core-shell nanoparticles for tumor-targeted delivery of Rapamycin.
3 Biotech. 2025 Jan;15(1):23. doi: 10.1007/s13205-024-04189-y. Epub 2024 Dec 25.
7
Recent developments in the identification and biosynthesis of antitumor drugs derived from microorganisms.
Eng Microbiol. 2022 Sep 3;2(4):100047. doi: 10.1016/j.engmic.2022.100047. eCollection 2022 Dec.
8
Hyperactive mTORC1 in striatum dysregulates dopamine receptor expression and odor preference behavior.
Front Neurosci. 2024 Aug 30;18:1461178. doi: 10.3389/fnins.2024.1461178. eCollection 2024.

本文引用的文献

1
Raptor is phosphorylated by cdc2 during mitosis.
PLoS One. 2010 Feb 12;5(2):e9197. doi: 10.1371/journal.pone.0009197.
2
The role of mTOR signaling in controlling mammalian life span: what a fungicide teaches us about longevity.
J Gerontol A Biol Sci Med Sci. 2010 Jun;65(6):580-9. doi: 10.1093/gerona/glp212. Epub 2010 Jan 18.
3
mTOR Ser-2481 autophosphorylation monitors mTORC-specific catalytic activity and clarifies rapamycin mechanism of action.
J Biol Chem. 2010 Mar 12;285(11):7866-79. doi: 10.1074/jbc.M109.096222. Epub 2009 Dec 18.
4
mTORC1-activated S6K1 phosphorylates Rictor on threonine 1135 and regulates mTORC2 signaling.
Mol Cell Biol. 2010 Feb;30(4):908-21. doi: 10.1128/MCB.00601-09. Epub 2009 Dec 7.
5
Rictor is a novel target of p70 S6 kinase-1.
Oncogene. 2010 Feb 18;29(7):1003-16. doi: 10.1038/onc.2009.401. Epub 2009 Nov 23.
6
TOR complex 2: a signaling pathway of its own.
Trends Biochem Sci. 2009 Dec;34(12):620-7. doi: 10.1016/j.tibs.2009.09.004. Epub 2009 Oct 28.
7
Regulation of mTOR complex 1 (mTORC1) by raptor Ser863 and multisite phosphorylation.
J Biol Chem. 2010 Jan 1;285(1):80-94. doi: 10.1074/jbc.M109.029637. Epub 2009 Oct 28.
8
RhoE inhibits 4E-BP1 phosphorylation and eIF4E function impairing cap-dependent translation.
J Biol Chem. 2009 Dec 18;284(51):35287-96. doi: 10.1074/jbc.M109.050120.
9
mTOR signaling at a glance.
J Cell Sci. 2009 Oct 15;122(Pt 20):3589-94. doi: 10.1242/jcs.051011.
10
TOR signaling in invertebrates.
Curr Opin Cell Biol. 2009 Dec;21(6):825-36. doi: 10.1016/j.ceb.2009.08.007. Epub 2009 Sep 19.

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