老年人群中黑色素瘤的经济负担:基于监测、流行病学和最终结果(SEER)-医疗保险数据的人群分析。
Economic burden of melanoma in the elderly population: population-based analysis of the Surveillance, Epidemiology, and End Results (SEER)--Medicare data.
作者信息
Seidler Anne M, Pennie Michelle L, Veledar Emir, Culler Steven D, Chen Suephy C
机构信息
Department of Dermatology, Emory University, 1639 Pierce Drive, Atlanta, GA 30322, USA.
出版信息
Arch Dermatol. 2010 Mar;146(3):249-56. doi: 10.1001/archdermatol.2009.389.
OBJECTIVE
To assess health care resources consumed by melanoma in the population 65 years or older, a group with comparatively poor outcomes.
DESIGN
Database analysis.
SETTING
The Surveillance, Epidemiology, and End Results (SEER)-Medicare-linked population-based database for fiscal years 1991 through 1996.
PARTICIPANTS
A total of 1858 subjects with pathological confirmation of melanoma.
MAIN OUTCOME MEASURES
Resource consumption was examined by stage and treatment phase. Outcomes were measured in monthly charges obtained from the data set and costs were estimated by application of cost to charge ratios. Annual resource consumption by melanoma in patients 65 years or older in the United States was also estimated by incorporation of published SEER cancer statistics.
RESULTS
Average monthly, per-patient melanoma charges were $2194 during the initial 4 months of treatment; they dropped by more than half to $902 during the interim phase, which varied in length depending on survival. Monthly charges increased to $3933 during the terminal 6 months of treatment. The estimated annual charge of treating melanoma in the population 65 years or older was $390 million. By using cost to charge ratios, we found the annual cost of melanoma to be up to $249 million and the per-patient lifetime costs to be $28 210 from the time of diagnosis to the time of death.
CONCLUSIONS
Melanoma care presents a significant economic burden in the elderly population, particularly in late-stage disease. If effective, prevention and early detection efforts may reduce the economic burden.
目的
评估65岁及以上人群中黑色素瘤所消耗的医疗保健资源,这是一组预后相对较差的人群。
设计
数据库分析。
设置
1991年至1996财政年度的监测、流行病学和最终结果(SEER)-医疗保险关联的基于人群的数据库。
参与者
共有1858名经病理证实为黑色素瘤的受试者。
主要观察指标
按分期和治疗阶段检查资源消耗情况。通过从数据集中获取的每月费用来衡量结果,并通过应用成本与收费比率来估计成本。还通过纳入已发表的SEER癌症统计数据来估计美国65岁及以上患者中黑色素瘤的年度资源消耗。
结果
在治疗的最初4个月,每位患者黑色素瘤的平均每月费用为2194美元;在中期阶段降至一半以上,为902美元,中期阶段的时长因生存情况而异。在治疗的最后6个月,每月费用增至3933美元。估计65岁及以上人群中治疗黑色素瘤的年度费用为3.9亿美元。通过使用成本与收费比率,我们发现黑色素瘤每年的成本高达2.49亿美元,从诊断到死亡每位患者的终身成本为28210美元。
结论
黑色素瘤治疗给老年人群带来了巨大的经济负担,尤其是在疾病晚期。如果有效,预防和早期检测措施可能会减轻经济负担。