Yabroff K Robin, Lamont Elizabeth B, Mariotto Angela, Warren Joan L, Topor Marie, Meekins Angela, Brown Martin L
Health Services and Economics Branch/Applied Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute, Executive Plaza North, Rm 4005, 6130 Executive Blvd, MSC 7344, Bethesda, MD 20892-7344, USA.
J Natl Cancer Inst. 2008 May 7;100(9):630-41. doi: 10.1093/jnci/djn103. Epub 2008 Apr 29.
Timely estimates of the costs of care for cancer patients are an important element in the formulation of national cancer programs and policies. We estimated net costs of care for elderly cancer patients in the United States for the 18 most prevalent cancers and for all other tumor sites combined.
We used Surveillance, Epidemiology, and End Results-Medicare files to identify 718,907 cancer patients and 1,623,651 noncancer control subjects. Within each tumor site, noncancer control subjects were matched to patients by sex, age group, geographic location, and phase of care (ie, initial, continuing, and last year of life). Costs of care were estimated for each phase by use of Medicare claims data from January 1, 1999, through December 31, 2003. Per-patient net costs of care were applied to the 5-year survival of cancer patients by phase of care to estimate 5-year costs of care and extrapolated to the elderly US Medicare population diagnosed with cancer in 2004.
Across tumor sites, mean net costs of care were highest in the initial and last year of life phases of care and lowest in the continuing phase. Mean 5-year net costs varied widely, from less than $20,000 for patients with breast cancer or melanoma of the skin to more than $40,000 for patients with brain or other nervous system, esophageal, gastric, or ovarian cancers or lymphoma. For elderly cancer patients diagnosed in 2004, aggregate 5-year net costs of care to Medicare were estimated to be approximately $21.1 billion. Costs to Medicare were highest for lung, colorectal, and prostate cancers, reflecting underlying incidence, stage distribution at diagnosis, survival, and phase-specific costs for these tumor sites.
The costs of cancer care to Medicare are substantial and vary by tumor site, phase of care, stage at diagnosis, and survival.
及时估算癌症患者的护理成本是制定国家癌症计划和政策的重要因素。我们估算了美国老年癌症患者18种最常见癌症以及所有其他肿瘤部位合并的护理净成本。
我们使用监测、流行病学和最终结果-医疗保险文件来识别718,907名癌症患者和1,623,651名非癌症对照对象。在每个肿瘤部位内,根据性别、年龄组、地理位置和护理阶段(即初始阶段、持续阶段和生命的最后一年)将非癌症对照对象与患者进行匹配。利用1999年1月1日至2003年12月31日的医疗保险索赔数据估算每个阶段的护理成本。将每位患者的护理净成本应用于癌症患者不同护理阶段的5年生存率,以估算5年护理成本,并推算至2004年被诊断患有癌症的美国老年医疗保险人群。
在各个肿瘤部位中,护理净成本均值在护理的初始阶段和生命的最后一年最高,在持续阶段最低。5年护理净成本均值差异很大,乳腺癌或皮肤黑色素瘤患者低于20,000美元,而脑癌或其他神经系统癌症、食管癌、胃癌或卵巢癌或淋巴瘤患者则超过40,000美元。对于2004年被诊断患有癌症的老年患者,医疗保险的5年护理净成本总计估计约为211亿美元。医疗保险费用最高的是肺癌、结直肠癌和前列腺癌,这反映了这些肿瘤部位的潜在发病率、诊断时的分期分布、生存率以及各阶段特定成本。
医疗保险的癌症护理成本很高,且因肿瘤部位、护理阶段、诊断分期和生存率而异。