1-(2-芳基乙基)四氢-6-羟基-1H-嘧啶-2-硫酮的分子内环化反应：取代基对反应活性的影响。
Intramolecular cyclization of 1-(2-arylethyl)tetrahydro-6-hydroxy-1H-pyrimidin-2-thiones: effect of substituents on reactivity.
机构信息
Omsk FM Dostoevsky State University, Mira Prospect 55A, Omsk 644077, Russia.
出版信息
Mol Divers. 2010 Aug;14(3):455-62. doi: 10.1007/s11030-010-9239-4. Epub 2010 Mar 16.
PMID:20232143
Abstract
Convenient synthetic procedures for 1,2,3,6,7, 11b-hexahydro-4H-pyrimido[6, 1 -a] isoquinolin-4-thiones and 2,3,6,7,12,12b-hexahydro-1H-pyrimido[1',6':1,2]pyrido[3,4-b]indole-4-thiones have been developed. Structural factors which influence on a cascade cyclization process have been elucidated.
摘要
已经开发出了方便的 1,2,3,6,7,11b-六氢-4H-嘧啶并[6,1-a]异喹啉-4-硫酮和 2,3,6,7,12,12b-六氢-1H-嘧啶并[1',6':1,2]吡啶并[3,4-b]吲哚-4-硫酮的合成方法。阐述了影响级联环化过程的结构因素。
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