体细胞核移植：利弊
Somatic cell nuclear transfer: pros and cons.
作者信息
Sumer Huseyin, Liu Jun, Tat Pollyanna, Heffernan Corey, Jones Karen L, Verma Paul J
机构信息
Monash Institute of Medical Research, Monash University, 27-31 Wright Street, Clayton VIC 3168, Australia.
出版信息
J Stem Cells. 2009;4(2):85-93.
Even though the technique of mammalian SCNT is just over a decade old it has already resulted in numerous significant advances. Despite the recent advances in the reprogramming field, SCNT remains the bench-mark for the generation of both genetically unmodified autologous pluripotent stem cells for transplantation and for the production of cloned animals. In this review we will discuss the pros and cons of SCNT, drawing comparisons with other reprogramming methods.
尽管哺乳动物体细胞核移植技术问世才十多年，但它已经带来了许多重大进展。尽管重编程领域最近取得了进展，但体细胞核移植仍然是用于移植的基因未修饰自体多能干细胞生成以及克隆动物生产的基准方法。在这篇综述中，我们将讨论体细胞核移植的优缺点，并与其他重编程方法进行比较。
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