Department of Urology, Korea University Medical Center, Seoul, Korea.
J Sex Med. 2011 Dec;8(12):3407-13. doi: 10.1111/j.1743-6109.2010.01748.x. Epub 2010 Mar 11.
Despites the debates on penile girth enhancement (PGE), demands for enhancement are increasing. Recently, various fillers have been widely used for soft tissue augmentation with proven efficacy and safety.
To identify the feasibility and efficacy of PGE by injection of filler.
Fifty patients with subjective small penis who visited Korea University Guro outpatient clinic were enrolled and prospectively followed. Restylane Sub-Q (Q-med, Upssala, Sweden) was injected into the fascial layer of penile body via 21G cannula with "Back & Forth Technique" and homogenized with a roller.
From April 2006 to February 2008, 50 patients were enrolled and 41 patients were followed until 18 months after PGE. Changes in penile girth at midshaft were measured by tapeline at 1 and 18 months. Patient's visual estimation of residual volume (Gr 0-4), patient's satisfaction (Gr 0-4), and any adverse reactions were also evaluated.
Mean injected volume was 20.56 cc (18-22). Compared with basal girth of 7.48 ± 0.35 cm, maximal circumference was significantly increased to 11.41 ± 0.34 cm at 1 month (P < 0.0001) and maintained as 11.26 ± 0.33 cm until 18 months. In patient's visual estimation, two patients complained the decrease as Gr 3 with focal depression at 1 month. At 18 months, all patients answered as Gr 4 without asymmetry. Patient's and partner's satisfaction score was 3.71 ± 0.46 and 3.65 ± 0.48 at 1 month and 3.34 ± 0.53 and 3.38 ± 0.49 at 18 months. There were no inflammatory signs or serious adverse reactions in all cases.
Considering the property of material, methods, and follow-up results of 18 months, PGE using filler is a very effective and safe technique for penile augmentation.
尽管关于阴茎周长增大（PGE）的争议不断，但对增大的需求仍在增加。最近，各种填充物已广泛用于软组织增大，具有已证实的疗效和安全性。
通过注射填充物来确定 PGE 的可行性和疗效。
50 名主观上认为阴茎较小的患者在韩国大学古罗门诊就诊，他们被纳入研究并进行前瞻性随访。通过 21G 套管用“来回技术”将瑞蓝（Q- Med，瑞典乌普萨拉）注射到阴茎体的筋膜层，并使用滚轮将其均匀化。
2006 年 4 月至 2008 年 2 月，共纳入 50 名患者，41 名患者随访至 PGE 后 18 个月。通过测线在 1 个月和 18 个月时测量阴茎中段的周长变化。患者对残留体积的视觉评估（Gr0-4）、患者满意度（Gr0-4）和任何不良反应也进行了评估。
平均注射量为 20.56cc（18-22cc）。与基础周长 7.48±0.35cm 相比，1 个月时最大周长显著增加至 11.41±0.34cm（P<0.0001），并在 18 个月时保持在 11.26±0.33cm。在患者的视觉评估中，2 名患者在 1 个月时因局部凹陷而抱怨减少至 Gr3。在 18 个月时，所有患者均无不对称性，回答为 Gr4。患者和伴侣的满意度评分为 1 个月时 3.71±0.46 和 3.65±0.48，18 个月时 3.34±0.53 和 3.38±0.49。所有病例均无炎症迹象或严重不良反应。
考虑到材料特性、方法和 18 个月的随访结果，使用填充物的 PGE 是一种非常有效和安全的阴茎增大技术。
