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起初是结肠切除术:家族性腺瘤性息肉病的当前手术选择。

In the beginning there was colectomy: current surgical options in familial adenomatous polyposis.

作者信息

McGrath Daniel R, Spigelman Allan D

机构信息

Discipline of Surgical Science, University of Newcastle, Australia.

出版信息

Hered Cancer Clin Pract. 2004 Nov 15;2(4):153-60. doi: 10.1186/1897-4287-2-4-153.

Abstract

Multiple colonic polyps, almost guaranteed colorectal cancer by the age of forty-five and an increased risk of non-colonic cancers characterise the autosomal dominant condition Familial Adenomatous Polyposis (FAP) 1. The patients and families faced with such a diagnosis present many difficult management challenges, both surgical and non-surgical. We discuss the current surgical options for treatment of the more significant manifestations of FAP arising in the colorectum and duodenum as well as desmoid disease.

摘要

多发性结肠息肉几乎可以确定到45岁时会发展为结直肠癌,并且患非结肠癌的风险增加,这是常染色体显性遗传病家族性腺瘤性息肉病(FAP)的特征。面临这种诊断的患者和家庭在手术和非手术管理方面都面临许多难题。我们讨论了目前针对结直肠癌、十二指肠癌以及硬纤维瘤病等FAP更严重表现的手术治疗选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f725/2840002/0ae8e172cb4b/1897-4287-2-4-153-1.jpg

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