Ozyazicioglu A, Yalcinkaya S, Vural A H, Yumun G, Bozkurt O
Department of Cardiovascular Surgery, Bursa Yuksek Ihtisas Training and Research Hospital, Bursa, Turkey.
J Int Med Res. 2010 Jan-Feb;38(1):202-7. doi: 10.1177/147323001003800123.
Metabolic syndrome is a well-known cardiovascular risk factor closely related to increased insulin resistance. This study assessed the effects of metabolic syndrome on early post-operative mortality and morbidity in 100 coronary artery bypass graft (CABG) patients: 50 patients with and 50 without metabolic syndrome. A total of 17 patients were excluded from the analysis as they did not attend follow-up, leaving 51 males (61.4%) and 32 (38.6%) females of mean +/- SD age 60.02 +/- 9.76 years for analysis. Diabetes, hypertension and a high body mass index were significantly more common in patients with metabolic syndrome. A statistically significant relationship was found between metabolic syndrome and surgical wound infection. Non-significant positive correlations were found between metabolic syndrome and post-operative atrial fibrillation, surgical revision due to haemorrhage, ventricular tachycardia and ventricular fibrillation, and prolonged intubation. In conclusion, metabolic syndrome did not affect mortality, but did increase the risk of post-operative surgical wound infection.
代谢综合征是一种众所周知的心血管危险因素，与胰岛素抵抗增加密切相关。本研究评估了代谢综合征对100例冠状动脉旁路移植术（CABG）患者术后早期死亡率和发病率的影响：50例患有代谢综合征，50例未患代谢综合征。共有17例患者因未参加随访而被排除在分析之外，剩余51例男性（61.4%）和32例女性（38.6%），平均年龄±标准差为60.02±9.76岁，纳入分析。糖尿病、高血压和高体重指数在代谢综合征患者中更为常见。代谢综合征与手术伤口感染之间存在统计学显著关系。代谢综合征与术后房颤、因出血进行的手术修正、室性心动过速和室颤以及插管时间延长之间存在非显著正相关。总之，代谢综合征不影响死亡率，但确实增加了术后手术伤口感染的风险。
