Tubura E
Toneyama National Hospital, Osaka, Japan.
Kekkaku. 1991 Feb;66(2):95-9.
The 445 cases of pulmonary tuberculosis in compromised host were investigated. Summary of the analysed results were as follows; (1) The major underlying diseases of compromised hosts with tuberculosis were diabetes mellitus and various types of cancer. (2) The major risk factors for advancement of tuberculosis were malnutrition and iatrogenic suppressions due to long term use of corticosteroids and anticancer agents. (3) The patients with malnutrition in the compromised hosts showed poor prognosis. (4) The chest roentgenogram of tuberculous lesion was difficult to improve in these patients when their clinical stage of tuberculosis had been advanced at admission. (5) The diagnosis and management of pulmonary tuberculosis in compromised host remain as a serious problem in recent years.
对445例免疫功能低下宿主的肺结核病例进行了调查。分析结果总结如下：(1) 患有肺结核的免疫功能低下宿主的主要基础疾病是糖尿病和各类癌症。(2) 结核病进展的主要危险因素是营养不良以及长期使用皮质类固醇和抗癌药物导致的医源性免疫抑制。(3) 免疫功能低下宿主中营养不良的患者预后较差。(4) 当这些患者入院时结核病临床分期已进展时，其结核病灶的胸部X线片很难改善。(5) 近年来，免疫功能低下宿主肺结核的诊断和管理仍然是一个严重问题。
