Kawaharada Nobuyoshi, Ito Toshiro, Koyanagi Tetsuya, Harada Ryo, Hyodoh Hideki, Kurimoto Yoshihiko, Watanabe Atsushi, Higami Tetsuya
Department of Thoracic and Cardiovascular Surgery, Sapporo Medical University School of Medicine, South 1 West 16, Chuo-ku, Sapporo 060-8543, Japan.
Interact Cardiovasc Thorac Surg. 2010 Jun;10(6):986-90; discussion 990-1. doi: 10.1510/icvts.2009.219790. Epub 2010 Mar 16.
Open repair of aortic aneurysm causes spinal cord perfusion pressure to decrease due to the steal phenomenon from the bleeding of intercostal arteries and cross-clamping of the aorta. We attempted to perfuse the intercostal arteries for preoperative detection of the artery of Adamkiewicz using newly developed catheters. Fifteen patients underwent selective spinal perfusion with our original catheter as spinal protection during the procedure of distal descending thoracic aneurysm (DTA) or thoracoabdominal aortic aneurysm (TAAA) repair. Seven patients had distal DTA and eight had TAAA. Monitoring of motor evoked potential (MEP) was performed in all patients throughout the operation. The perfusion flow was 30-40 ml/min for each intercostal artery and was adjusted to keep the proximal circuit pressure at 150-200 mmHg. The average number of perfused intercostal arteries was 2.3 per patient and the number of intercostal arteries reimplanted per patient was 2.5. Intercostal arteries were reimplanted using an interpositional graft. MEPs were still observable after graft replacement in all patients and there were no cases of paraparesis/paraplegia. All patients were discharged ambulatory. Selective spinal perfusion maintains the quantity of total blood flow in the spinal cord and is very useful for reducing the incidence of ischemic injury of the spinal cord during operation.
由于肋间动脉出血和主动脉交叉钳夹导致的盗血现象,主动脉瘤开放修复会使脊髓灌注压降低。我们尝试使用新开发的导管对肋间动脉进行灌注,以在术前检测Adamkiewicz动脉。15例患者在远端降主动脉瘤(DTA)或胸腹主动脉瘤(TAAA)修复过程中,使用我们的原始导管进行选择性脊髓灌注作为脊髓保护措施。7例患者患有远端DTA,8例患有TAAA。所有患者在整个手术过程中均进行了运动诱发电位(MEP)监测。每条肋间动脉的灌注流量为30 - 40毫升/分钟,并进行调整以保持近端循环压力在150 - 2 mmHg。每位患者灌注的肋间动脉平均数量为2.3条,每位患者重新植入的肋间动脉数量为2.5条。使用间置移植物重新植入肋间动脉。所有患者在移植物置换后MEP仍可观察到,且无截瘫/偏瘫病例。所有患者均能步行出院。选择性脊髓灌注可维持脊髓总血流量,对降低手术期间脊髓缺血性损伤的发生率非常有用。