Hanafusa Y, Okada K, Mimura T, Kawanishi Y, Ozaki N, Yamashita T, Tsuji Y, Okita Y
Division of Cardiovascular, Thoracic, and Pediatric Surgery, Kobe University, Graduate School of Medicine, Kobe, Japan.
Kyobu Geka. 2004 Apr;57(4):313-8.
Spinal cord injury such as paraparesis and paraplegia remains one of the major concerns in surgery on the thoracoabdominal aortic aneurysm (TAAA). We utilize spinal cord protection including cerebrospinal fluid drainage (CSFD), adjuncts of aortic distal perfusion, reconstruction of the intercostal or lumbar arteries and deep hypothermia in TAAA repair. This report describes the results of surgical treatment for TAAA including postoperative neurological outcome. Between October 1999 and January 2004, 33 patients (mean age 66 years; range 26 to 81) underwent TAAA repair. Adamkiewicz artery could be detected using magnetic resonance angiography in 9 patients. CSFD was done in 20 patients. TAAA repair was achieved using adjuncts of aortic distal perfusion in 31 patients (partial cardiopulmonary bypass: 19, deep hypothermia: 9, left heart bypass: 3). We tried to reconstruct the intercostal or lumbar arteries which were located between Th8 and L2 as possible. Twenty-five patients underwent reconstruction of the intercostal or lumbar arteries. There were 6 hospital deaths. Postoperative spinal cord injury occurred in 4 patients (paraparesis: 1, paraplegia: 3). This clinical experience demonstrates that current technical strategies enable patients to undergo TAAA repair with acceptable early survival. However, despite aggressive spinal cord protection, few patients suffered from postoperative spinal cord injury. Future research should focus on spinal cord protection in patients with TAAA.
诸如截瘫和四肢瘫等脊髓损伤仍然是胸腹主动脉瘤(TAAA)手术中的主要问题之一。我们在TAAA修复术中采用了脊髓保护措施,包括脑脊液引流(CSFD)、主动脉远端灌注辅助、肋间或腰动脉重建以及深度低温。本报告描述了TAAA手术治疗的结果,包括术后神经功能结果。1999年10月至2004年1月期间,33例患者(平均年龄66岁;范围26至81岁)接受了TAAA修复术。9例患者可通过磁共振血管造影检测到Adamkiewicz动脉。20例患者进行了CSFD。31例患者在主动脉远端灌注辅助下完成了TAAA修复术(部分体外循环:19例,深度低温:9例,左心转流:3例)。我们尽可能尝试重建位于胸8和腰2之间的肋间或腰动脉。25例患者进行了肋间或腰动脉重建。有6例医院死亡病例。4例患者发生了术后脊髓损伤(截瘫:1例,四肢瘫:3例)。这一临床经验表明,当前的技术策略使患者能够接受TAAA修复术并获得可接受的早期生存率。然而,尽管采取了积极的脊髓保护措施,仍有少数患者遭受术后脊髓损伤。未来的研究应聚焦于TAAA患者的脊髓保护。