CwpFM（肠毒素 FM）是一种枯草芽孢杆菌潜在的细胞壁肽酶，与黏附、生物膜形成和毒力有关。
CwpFM (EntFM) is a Bacillus cereus potential cell wall peptidase implicated in adhesion, biofilm formation, and virulence.
机构信息
INRA, Unité MICALIS UMR-1319, Equipe GME, La Minière, 78285 Guyancourt, France.
出版信息
J Bacteriol. 2010 May;192(10):2638-42. doi: 10.1128/JB.01315-09. Epub 2010 Mar 16.
Abstract
Bacillus cereus EntFM displays an NlpC/P60 domain, characteristic of cell wall peptidases. The protein is involved in bacterial shape, motility, adhesion to epithelial cells, biofilm formation, vacuolization of macrophages, and virulence. These data provide new information on this, so far, poorly studied toxin and suggest that this protein is a cell wall peptidase, which we propose to rename CwpFM.
摘要
蜡样芽胞杆菌 EntFM 展示出 NlpC/P60 结构域，这是一种细胞壁肽酶的特征。该蛋白参与细菌形态、运动性、上皮细胞黏附、生物膜形成、巨噬细胞空泡化和毒力。这些数据为这种迄今为止研究甚少的毒素提供了新的信息，并表明该蛋白是一种细胞壁肽酶，我们建议将其重新命名为 CwpFM。
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