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心血管疾病家族史对临床医生预防性建议及无心血管疾病患者后续依从性的影响。

Influence of family history of cardiovascular disease on clinicians' preventive recommendations and subsequent adherence of patients without cardiovascular disease.

作者信息

Zlot A I, Valdez R, Han Y, Silvey K, Leman R F

机构信息

Oregon Genetics Program, Public Health Division, Oregon Department of Human Services, Portland, OR 97232, USA.

出版信息

Public Health Genomics. 2010;13(7-8):457-66. doi: 10.1159/000293991. Epub 2010 Mar 17.

Abstract

BACKGROUND

Family history of cardiovascular disease (CVD) is an independent risk factor for CVD. Therefore, efforts to prevent CVD among asymptomatic persons with a family history are warranted. Little is known about preventive recommendations clinicians offer their patients with a family history of CVD, and adherence to preventive recommendations by patients at risk for CVD has not been well described.

METHODS

We used the 2007 Oregon Behavioral Risk Factor Surveillance System to evaluate among 2,566 adults without CVD associations between family history of CVD and (a) clinician recommendations; (b) perceived risk of developing CVD; (c) adoption of preventive and screening behaviors; and (d) risk factors of CVD.

RESULTS

Compared with adults with no family history of CVD, those with a family history reported that their clinician was more likely to ask about their family history information (OR = 2.6; 95% CI, 1.9-3.4), discuss the risk of developing CVD (OR = 2.0; 95% CI, 1.6-2.5), and make recommendations to prevent CVD (OR = 2.1; 95% CI, 1.7-2.7). Family history and clinician recommendations were associated with a higher likelihood of reported changes in diet or physical activity to prevent CVD (OR = 2.7; 95% CI, 2.3-3.2). Persons with a family history of CVD were more likely to report having high cholesterol, having high blood pressure, taking aspirin, and having had their cholesterol checked.

CONCLUSION

The presence of a family history of CVD appears to prompt clinicians to recommend preventive changes and may motivate patients without CVD to adopt these recommendations.

摘要

背景

心血管疾病(CVD)家族史是CVD的独立危险因素。因此,有必要对有家族史的无症状人群采取预防CVD的措施。对于临床医生向有CVD家族史的患者提供的预防建议知之甚少,而且有CVD风险的患者对预防建议的依从性也没有得到很好的描述。

方法

我们使用2007年俄勒冈州行为危险因素监测系统,在2566名无CVD的成年人中评估CVD家族史与以下因素之间的关联:(a)临床医生的建议;(b)患CVD的感知风险;(c)采取预防和筛查行为;(d)CVD危险因素。

结果

与无CVD家族史的成年人相比,有家族史的成年人报告称,他们的临床医生更有可能询问其家族史信息(比值比[OR]=2.6;95%置信区间[CI],1.9-3.4),讨论患CVD的风险(OR=2.0;95%CI,1.6-2.5),并提出预防CVD的建议(OR=2.1;95%CI,1.7-2.7)。家族史和临床医生的建议与报告为预防CVD而改变饮食或身体活动的可能性较高相关(OR=2.7;95%CI,2.3-3.2)。有CVD家族史的人更有可能报告患有高胆固醇、高血压、服用阿司匹林以及接受过胆固醇检查。

结论

CVD家族史的存在似乎促使临床医生建议进行预防性改变,并可能促使无CVD的患者采纳这些建议。

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