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将光滑双脐螺卵亚慢性暴露于阿里丹宁和氯硝柳胺。

Subchronic exposure of Biomphalaria glabrata eggs to aridanin and niclosamide.

作者信息

Adewunmi C O

机构信息

Danish Bilharziasis Laboratory, Charlottenlund.

出版信息

J Ethnopharmacol. 1991 Feb;31(2):209-16. doi: 10.1016/0378-8741(91)90006-y.

DOI:10.1016/0378-8741(91)90006-y
PMID:2023429
Abstract

Treatment of 3-day-old Biomphalaria glabrata eggs with aridanin caused a knock-down effect on the prehatch snails, making this group the most susceptible. The development and hatching of 0- to 1-day-old eggs could not be prevented but was prolonged by continuous exposure to aridanin (0.5-10 mg/l). Prehatch snails were less susceptible than juvenile and adult snails. Niclosamide (0.625-0.35 mg/l) arrested the development of B. glabrata. The results predict a poor action of aridanin as an ovicidal agent in the control of snail intermediate hosts of schistosomiasis.

摘要

用阿瑞丹宁处理3日龄的光滑双脐螺卵,对孵化前的蜗牛产生了击倒效应,使该组成为最易感组。0至1日龄卵的发育和孵化无法阻止,但持续暴露于阿瑞丹宁(0.5 - 10毫克/升)会使其延长。孵化前的蜗牛比幼螺和成螺更不易感。氯硝柳胺(0.625 - 0.35毫克/升)可阻止光滑双脐螺的发育。结果表明,阿瑞丹宁作为杀卵剂在控制血吸虫病中间宿主蜗牛方面效果不佳。

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