Bourdeanu Laura, Luu Thehang
Department of Medical Oncology, City of Hope, National Medical Center and Beckman Research Institute, Duarte, California 91010, USA.
J Am Acad Nurse Pract. 2010 Mar;22(3):140-3. doi: 10.1111/j.1745-7599.2009.00486.x.
To report a case of arterial thrombosis in a 63-year-old female undergoing treatment with multiagent chemotherapy for breast cancer. An overview of the prevalence and pathogenesis of the disorder, clinical diagnosis, and treatment are discussed.
Case report, diagnostic evidence, and scientific literature.
Arterial thrombosis is an extremely rare complication of multichemotherapy treatment of breast cancer. Although the risk of arterial thromboembolism appears to be low, it can have devastating complications that result in significant morbidities and, sometimes, death.
As the risk of arterial thrombosis is low, many healthcare providers may not be aware of this potentially serious complication. Thrombosis prophylaxis should be considered for patients with risk factors. In cases where arterial thrombosis occurs, immediate thrombolitic therapy or operative intervention should be considered.
报告一例63岁接受多药联合化疗治疗乳腺癌的女性发生动脉血栓形成的病例。讨论该疾病的患病率、发病机制、临床诊断及治疗概况。
病例报告、诊断证据及科学文献。
动脉血栓形成是乳腺癌多药化疗极其罕见的并发症。尽管动脉血栓栓塞风险似乎较低,但可引发严重并发症,导致显著的发病情况,有时甚至死亡。
由于动脉血栓形成风险较低,许多医疗服务提供者可能未意识到这一潜在严重并发症。对于有风险因素的患者应考虑进行血栓预防。在发生动脉血栓形成的病例中,应考虑立即进行溶栓治疗或手术干预。