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与乳腺癌辅助化疗相关的动脉血栓形成:一例报告

Arterial thrombosis associated with adjuvant chemotherapy for breast cancer: a case report.

作者信息

Bourdeanu Laura, Luu Thehang

机构信息

Department of Medical Oncology, City of Hope, National Medical Center and Beckman Research Institute, Duarte, California 91010, USA.

出版信息

J Am Acad Nurse Pract. 2010 Mar;22(3):140-3. doi: 10.1111/j.1745-7599.2009.00486.x.

Abstract

PURPOSE

To report a case of arterial thrombosis in a 63-year-old female undergoing treatment with multiagent chemotherapy for breast cancer. An overview of the prevalence and pathogenesis of the disorder, clinical diagnosis, and treatment are discussed.

DATA SOURCES

Case report, diagnostic evidence, and scientific literature.

CONCLUSIONS

Arterial thrombosis is an extremely rare complication of multichemotherapy treatment of breast cancer. Although the risk of arterial thromboembolism appears to be low, it can have devastating complications that result in significant morbidities and, sometimes, death.

IMPLICATIONS FOR PRACTICE

As the risk of arterial thrombosis is low, many healthcare providers may not be aware of this potentially serious complication. Thrombosis prophylaxis should be considered for patients with risk factors. In cases where arterial thrombosis occurs, immediate thrombolitic therapy or operative intervention should be considered.

摘要

目的

报告一例63岁接受多药联合化疗治疗乳腺癌的女性发生动脉血栓形成的病例。讨论该疾病的患病率、发病机制、临床诊断及治疗概况。

资料来源

病例报告、诊断证据及科学文献。

结论

动脉血栓形成是乳腺癌多药化疗极其罕见的并发症。尽管动脉血栓栓塞风险似乎较低,但可引发严重并发症,导致显著的发病情况,有时甚至死亡。

对实践的启示

由于动脉血栓形成风险较低,许多医疗服务提供者可能未意识到这一潜在严重并发症。对于有风险因素的患者应考虑进行血栓预防。在发生动脉血栓形成的病例中,应考虑立即进行溶栓治疗或手术干预。

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