Romanos Georgios E, Brink Birgit
Divisions of Periodontology and General Dentistry, Eastman Institute for Oral Health, Unversity of Rochester, NY, USA.
Gen Dent. 2010 Mar-Apr;58(2):e68-73.
In recent years, the combination of laser light and photosensitizer known as photodynamic therapy (PDT) has been used in periodontal therapy. However, there are not enough clinical studies to fully evaluate the effects of PDT on the periodontal tissues. This microbiological study examined the effects of PDT on the periodontal bacteria in combination with scaling and root planing (SRP) in the same group of patients by randomly selecting PDT or SRP for use in different quadrants of the mouth. For the present study, PDT was compared with a diode laser (980 nm) and an Nd:YA G laser (1,064 nm). Microbiological samples were examined and evaluated over a period of three months. Significant bacterial reduction has been observed in all cases. The diode laser with SRP presented long-term positive results, while PDT showed a significant bacteria reduction during the entire observation period.
近年来，激光与光敏剂相结合的光动力疗法（PDT）已被用于牙周治疗。然而，尚无足够的临床研究来全面评估PDT对牙周组织的影响。这项微生物学研究通过在同一组患者的不同象限随机选择使用PDT或龈上洁治术和根面平整术（SRP），研究了PDT联合SRP对牙周细菌的影响。在本研究中，将PDT与二极管激光（980纳米）和钕：钇铝石榴石激光（1064纳米）进行了比较。在三个月的时间里对微生物样本进行了检查和评估。在所有病例中均观察到细菌显著减少。二极管激光联合SRP呈现出长期的积极效果，而PDT在整个观察期内显示出细菌显著减少。
