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泰国初级保健单位护士实施的动机增强疗法对危险饮酒者的有效性随机对照试验。

RCT of effectiveness of motivational enhancement therapy delivered by nurses for hazardous drinkers in primary care units in Thailand.

机构信息

Department of Social Medicine, Chonburi Hospital and Medical Education Center, Chonburi, 20000, Thailand.

出版信息

Alcohol Alcohol. 2010 May-Jun;45(3):263-70. doi: 10.1093/alcalc/agq013. Epub 2010 Mar 17.

Abstract

AIMS

To determine the effectiveness of Motivational Enhancement Therapy (MET) for hazardous drinkers in Primary Care Unit (PCU) settings in rural Thailand.

METHODS

A randomized controlled trial was conducted in eight PCUs in Ubonratchatanee and Chachoengsao provinces in Thailand. Hazardous drinkers were identified using the World Health Organization-recommended Alcohol Use Disorder Identification Test. Of 117 eligible participants (91% male), 59 were randomized to the intervention group to receive MET in three individual appointments with a trained nurse and 58 to an assessment-only control group. Outcome evaluations were carried out after 6 weeks, 3 months and 6 months.

RESULTS

Follow-up data were available on 84, 94 and 91% of subjects, respectively, at the three intervals. Self-reported drinks per drinking day, frequency of hazardous drinking assessed either on a daily or weekly basis, and of binge drinking sessions were reduced in the intervention group more than in the control group (P < 0.05) after both 3 and 6 months. The groups did not generally differ at 6 weeks. However, although self-reported consumption in both groups fell from baseline to 6-month follow-up, serum gamma-glutamyl transferase increased in both groups, which raises doubts about the validity of this marker in this sample and/or the validity of the self-reported data in this study.

CONCLUSION

MET delivered by nurses in PCUs in Thailand appears to be an effective intervention for male hazardous drinkers. Uncertainties about the validity of self-reported data jeopardize the safety of this conclusion.

摘要

目的

在泰国农村的基层医疗单位(PCU)环境中,确定动机增强疗法(MET)对危险饮酒者的有效性。

方法

在泰国乌汶叻差他尼府和乍都乍府的 8 个 PCU 中进行了一项随机对照试验。使用世界卫生组织推荐的酒精使用障碍识别测试来确定危险饮酒者。在 117 名符合条件的参与者(91%为男性)中,59 名被随机分配到干预组,接受由经过培训的护士进行的 3 次个体预约的 MET,58 名被分配到仅评估对照组。在 6 周、3 个月和 6 个月后进行了结果评估。

结果

在这三个时间间隔中,分别有 84%、94%和 91%的受试者可获得随访数据。与对照组相比,干预组在 3 个月和 6 个月后,自我报告的每日饮酒量、每日或每周评估的危险饮酒频率以及狂欢饮酒次数均有所减少(P<0.05)。两组在 6 周时通常没有差异。然而,尽管两组的自我报告饮酒量均从基线降至 6 个月随访时有所下降,但两组的血清γ-谷氨酰转移酶均有所升高,这让人对该样本中该标志物的有效性和/或该研究中自我报告数据的有效性产生了怀疑。

结论

在泰国的 PCU 中,由护士提供的 MET 似乎是一种有效的干预措施,适用于男性危险饮酒者。自我报告数据的有效性存在不确定性,这危及到这一结论的安全性。

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