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[24小时血压监测在高血压所致靶器官损害检测中的重要性]

[Importance of 24-hour blood pressure monitoring in detection of hypertension-induced end organ damage].

作者信息

Schächinger H, Schmieder R E

机构信息

Medizinische Universitätsklinik, (Vegetatives Nervensystem und Psychosomatik) Bonn-Venusberg.

出版信息

Z Kardiol. 1991;80 Suppl 1:41-7.

PMID:2024533
Abstract

Casual blood pressure does not provide an adequate estimation for the hemodynamic load of 24 hours upon the cardiovascular system. Hence, cardiovascular complications are loosely correlated to casual blood pressure measurements in arterial hypertension. In contrast, ambulatory blood pressure measurements have been repeatedly found to be closely related to signs of target organ damage such as left ventricular hypertrophy, hypertensive nephropathy and impaired arterial compliance. Furthermore, monitoring of blood pressure over 24 hours allows assessment of hazardous nocturnal declines in perfusion pressure with the risk of fatal coronary or cerebrovascular events. A blunted nocturnal decline in blood pressure has been suggested to indicate secondary forms of arterial hypertension or severe hypertensive disease. In conclusion, ambulatory blood pressure monitoring, nowadays reliably assessed by non-invasive tools, improves the estimation of the hemodynamic load imposed on the cardiovascular system and thereby the risks attributed to arterial hypertension.

摘要

偶测血压不能充分评估24小时内心血管系统的血流动力学负荷。因此,在动脉高血压中,心血管并发症与偶测血压值的相关性较弱。相比之下,动态血压监测已多次被发现与靶器官损害的体征密切相关,如左心室肥厚、高血压肾病和动脉顺应性受损。此外,24小时血压监测可以评估夜间灌注压的危险下降情况,以及发生致命性冠状动脉或脑血管事件的风险。血压夜间下降减弱被认为提示继发性动脉高血压或严重高血压疾病。总之,如今通过非侵入性工具可可靠评估的动态血压监测,改善了对心血管系统血流动力学负荷的评估,从而也改善了对动脉高血压所致风险的评估。

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