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高危患者术后肺部并发症及肺功能:全身麻醉下上腹部手术后三种物理治疗方案的比较

Postoperative pulmonary complications and lung function in high-risk patients: a comparison of three physiotherapy regimens after upper abdominal surgery in general anesthesia.

作者信息

Christensen E F, Schultz P, Jensen O V, Egebo K, Engberg M, Grøn I, Juhl B

机构信息

Department of Anesthesiology, University Hospital of Aarhus, Denmark.

出版信息

Acta Anaesthesiol Scand. 1991 Feb;35(2):97-104. doi: 10.1111/j.1399-6576.1991.tb03255.x.

Abstract

The effect of three postoperative regimens of respiratory therapy on pulmonary complications and lung function was compared in high-risk patients. Fifty-one patients were randomized to: 1) conventional chest physiotherapy alone (PHYS), 2) chest physiotherapy and positive expiratory pressure (PEP), or 3) chest physiotherapy with both positive expiratory pressure and inspiratory resistance (RMT). Treatments were given twice daily by a physiotherapist and self-administered. The incidence of postoperative pulmonary complications (PPC) was respectively, 71%, 76% and 65% in the PHYS-, PEP- and RMT-groups. The incidence of PPC requiring treatment with antibiotic, bronchodilator or supplementary oxygen according to the existing clinical practice was 47%, 47% and 29%. The incidence of atelectasis was 65%, 64% and 60% and of pneumonia 29%, 35% and 6%. There was no difference between the groups, except for a tendency to a lower frequency of pneumonia in the RMT-group. Postoperatively forced vital capacity (FVC) decreased to mean 54%, forced expired volume in 1 s to 48% and functional residual capacity to 76% of preoperative values. Arterial oxygen tension (PaO2) declined to mean 8.1 kPa and arterial saturation (SaO2) to 89%. There was no difference between the groups except for FVC, PaO2 and SaO2 (P = 0.008, P = 0.008 and P = 0.002), which showed the least decrease in the RMT-group. None of the regimens could be considered as satisfactory concerning the prevention of PPC, but RMT seemed to be the most efficient. Insufficient self-administration of treatment was probably one of the causes of the overall high incidence of PPC in this study.

摘要

在高危患者中比较了三种术后呼吸治疗方案对肺部并发症和肺功能的影响。51例患者被随机分为:1)单纯传统胸部物理治疗(PHYS),2)胸部物理治疗加呼气末正压(PEP),或3)胸部物理治疗加呼气末正压和吸气阻力(RMT)。治疗由物理治疗师每天进行两次并可自行操作。PHYS组、PEP组和RMT组术后肺部并发症(PPC)的发生率分别为71%、76%和65%。根据现有临床实践,需要使用抗生素、支气管扩张剂或补充氧气治疗的PPC发生率分别为47%、47%和29%。肺不张的发生率分别为65%、64%和60%,肺炎的发生率分别为29%、35%和6%。除RMT组肺炎发生率有降低趋势外,各组之间无差异。术后用力肺活量(FVC)降至术前值的平均54%,1秒用力呼气量降至48%,功能残气量降至76%。动脉血氧分压(PaO2)降至平均8.1 kPa,动脉血氧饱和度(SaO2)降至89%。除FVC、PaO2和SaO2外(P = 0.008、P = 0.008和P = 0.002),各组之间无差异,其中RMT组下降最少。就预防PPC而言,没有一种方案被认为是令人满意的,但RMT似乎是最有效的。治疗的自行操作不足可能是本研究中PPC总体发生率高的原因之一。

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