Demin N N, Rubinskaia N L
Fiziol Zh SSSR Im I M Sechenova. 1977 Dec;63(12):1638-43.
In rats, administration of anticholinesterase drugs (both the penetrating blood-brain barrier armin and the nonpenetrating preparation Gd-42) prevented the decrease of protein content in the neurons and glia of the supraoptic nucleus, as well as of RNA content in the neurons which usually occurred in intact animals after 24-hr deprivation of the REM sleep by the Jouvet method (also with partial disturbance of the slow wave phase).
在大鼠中,给予抗胆碱酯酶药物(能穿透血脑屏障的氨基药物和不能穿透的制剂Gd - 42)可防止视上核神经元和神经胶质中蛋白质含量的降低,以及神经元中RNA含量的降低,而在通过茹韦法剥夺24小时快速眼动睡眠(同时慢波相也有部分紊乱)后,完整动物中通常会出现这种降低。